Evidence map›Paper›PMID 31774394›Full record

ArticleeLife2019

Real time dynamics of Gating-Related conformational changes in CorA.

Martina Rangl, Nicolaus Schmandt, Eduardo Perozo, Simon Scheuring

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Conformational ensembles of the magnesium channel CorA reveal structural basis for channel gating.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Structure and function of the human mitochondrial MRS2 channel.Nature structural & molecular biology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Molecular basis of MgNature communications · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. MgeLife · 2022
    Article
  11. Editorial: Structural dynamics of membrane proteins, Volume II.Frontiers in molecular biosciences · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martina RanglDepartment of Anesthesiology, Weill Cornell Medical College, New York, United States.
Nicolaus SchmandtDepartment of Biochemistry and Molecular Biophysics, The University of Chicago, Chicago, United States.
Eduardo PerozoDepartment of Biochemistry and Molecular Biophysics, The University of Chicago, Chicago, United States.ORCID 0000-0001-7132-2793
Simon ScheuringDepartment of Anesthesiology, Weill Cornell Medical College, New York, United States.ORCID 0000-0003-3534-069X

Funding

Enabling physical stimuli in the study of structural dynamics: The sensory ion channelsDP1AT010874 · NCCIH · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHEURING, SIMON · 2019 to 2023
$5.9M
Structural dynamics in cyclic nucleotide-modulated channelsR01GM124451 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI NIMIGEAN, CRINA M · 2017 to 2024
$3.2M
Structural basis of Mg2+ homeostasis - Equipment SupplementR01GM120561 · NIGMS · UNIVERSITY OF CHICAGO · PI PEROZO, EDUARDO A · 2017 to 2020
$1.4M
NCCIH NIH HHS DP1 AT010874NIGMS NIH HHS R01 GM120561NIH HHS DP1AT010874NIH HHS R01GM120561NIH HHS R01GM124451
6 · The paper itself

Abstract

CorA, a divalent-selective channel in the metal ion transport superfamily, is the major Mg

Indexed as

Molecular Dynamics SimulationProtein ConformationAnimalsBacterial ProteinsCation Transport ProteinsCrystallography, X-RayFemaleIon Channel GatingIon TransportMagnesiumMicroscopy, Atomic ForceOocytesThermotoga maritimaXenopus laevisBacterial ProteinsCation Transport ProteinsMagnesiumAFMCorAion channelsmembrane transportmolecular biophysicssingle moleculestructural biologyT. maritima

Identifiers

PMID31774394
PMCPMC6927688

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.