Evidence map›Paper›PMID 31774301›Full record

ArticleBioTechniques2020

An efficient and novel technology for the extraction of parasite genomic DNA from whole blood or culture.

David J Clark, Catherine M Moore, Marc Flanagan, Katrien Van Bocxlaer, Evangelia-Theophano Piperaki, Vanessa Yardley, Simon L Croft, John Tyson, Sam P Whitehouse, Jonathan O'Halloran and 2 more

Open access · goldAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BioTechniques, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Outbreak ofFrontiers in immunology · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

David J ClarkCentre for Diagnostics & Antimicrobial Resistance, Institute for Infection & Immunity, St George's University of London, Cranmer Terrace, London, SW17 0RE, UK.ORCID 0000-0003-3677-0034
Catherine M MooreCentre for Diagnostics & Antimicrobial Resistance, Institute for Infection & Immunity, St George's University of London, Cranmer Terrace, London, SW17 0RE, UK.
Marc FlanaganQuantuMDx, Newcastle upon Tyne, NE1 2JQ, UK.
Katrien Van BocxlaerInfection & Immunity Department, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Evangelia-Theophano PiperakiInfection & Immunity Department, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Vanessa YardleyInfection & Immunity Department, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
Simon L CroftInfection & Immunity Department, Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
John TysonQuantuMDx, Newcastle upon Tyne, NE1 2JQ, UK.
Sam P WhitehouseQuantuMDx, Newcastle upon Tyne, NE1 2JQ, UK.
Jonathan O'HalloranQuantuMDx, Newcastle upon Tyne, NE1 2JQ, UK.
Sanjeev KrishnaCentre for Diagnostics & Antimicrobial Resistance, Institute for Infection & Immunity, St George's University of London, Cranmer Terrace, London, SW17 0RE, UK.
Henry M StainesCentre for Diagnostics & Antimicrobial Resistance, Institute for Infection & Immunity, St George's University of London, Cranmer Terrace, London, SW17 0RE, UK.
London School of Hygiene & Tropical Medicine · GBQuantuMDx (United Kingdom) · GBSt George's, University of London · GB

Funding

Medical Research Council MC_PC_14111Wellcome Trust 204809Wellcome Trust 204809/Z/16/Z
6 · The paper itself

Abstract

The aim of this study was to assess pathogen DNA extraction with a new spin column-based method (DNA-XT). DNA from either whole-blood samples spiked with

Indexed as

DNA, ProtozoanGenome, ProtozoanHumansLeishmania donovaniPlasmodium falciparumDNA, ProtozoanblooddiagnosticsDNA extractionLeishmaniamalariaPCRPlasmodium

Identifiers

PMID31774301
PMCPMC7115988
OpenAlexW2991033857

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.