Evidence map›Paper›PMID 31774236›Full record

ArticleStem cells translational medicine2020

Two-year outcomes of infants enrolled in the first-in-human study of amnion cells for bronchopulmonary dysplasia.

Atul Malhotra, Rebecca Lim, Joanne C Mockler, Euan M Wallace

Open access · goldAbstract read
In one paragraph

Article in Stem cells translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Stem/Progenitor Cells and Related Therapy in Bronchopulmonary Dysplasia.International journal of molecular sciences · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. A protocol for cell therapy infusion in neonates.Stem cells translational medicine · 2021
    Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Atul MalhotraMonash Newborn, Monash Children's Hospital, Clayton, Victoria, Australia.ORCID 0000-0001-9664-4182
Rebecca LimThe Ritchie Centre, Hudson Institute of Medical Research, Monash University, Clayton, Victoria, Australia.ORCID 0000-0002-0410-497X
Joanne C MocklerDepartment of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia.
Euan M WallaceThe Ritchie Centre, Hudson Institute of Medical Research, Monash University, Clayton, Victoria, Australia.
Hudson Institute of Medical Research · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported on the immediate safety and neonatal outcomes of six premature infants with severe bronchopulmonary dysplasia (BPD) who were administered human amnion epithelial cells (hAECs). One infant died in the neonatal period due to unrelated causes. In this study, we aimed to assess the long-term safety and follow-up outcomes of the five surviving infants until 2 years corrected age (CA). hAECs were administered intravenously at a dose of 1 × 10

Indexed as

AmnionBronchopulmonary DysplasiaHumansInfantInfant, NewbornTime FactorsTreatment Outcomelong-termpretermsafetystem celltumor

Identifiers

PMID31774236
PMCPMC7031636
OpenAlexW2991510220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.