ArticleJournal of the American Chemical Society2019
Azulene-Derived Fluorescent Probe for Bioimaging: Detection of Reactive Oxygen and Nitrogen Species by Two-Photon Microscopy.
Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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Who cites it
35 citing papers in PubMed, 164 citations in OpenAlex.
- Synthesis of azulene fluorophores reveals structure-property relationships.Organic chemistry frontiers : an international journal of organic chemistry · 2026Article
- Guaiazulene-Based 2‑Hydrazinylpyridine Probe (ACS omega · 2026Article
- Cycloazulenylene.Angewandte Chemie (International ed. in English) · 2026Article
- Recent Advances in Organic Donor-Acceptor Two-Photon Absorption Materials: Mechanisms, Molecular Design, and Applications.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Decarbonylation Enables Chemodivergent Access to Guaiazulene-3-Oxalic and -Carboxylic Acid Derivatives.The Journal of organic chemistry · 2026Article
- Penetration depth of cold atmospheric plasma into biological tissue: a review.Frontiers in bioengineering and biotechnology · 2026Review
- Vitamin D-loaded lipid nanoparticles: antioxidant properties, preparation, optimization, and in vitro characterization.Drug delivery and translational research · 2025Article
- HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Multiplex imaging of amyloid-β plaques dynamics in living brains with quinoline-malononitrile-based probes.Nature biomedical engineering · 2025Article
- Rhodium-Catalyzed Intermolecular Arylative [2 + 2 + 1] Annulation-Oxidation to Produce Electron-Deficient Azulene-Embedded Polycyclic Aromatic Hydrocarbons.Angewandte Chemie (International ed. in English) · 2025Article
- Synthesis and resolution of a 1,1'-biazulene analogue of BINOL.RSC advances · 2025Article
- Near-Infrared Bioimaging Using Two-photon Fluorescent Probes.Advanced healthcare materials · 2025Review
- Chemistry and properties of fluorescent pyrazole derivatives: an approach to bioimaging applications.RSC advances · 2024Review
- Amphiphilic Azulene-Based Fluorescent Probe for Simultaneous Monitoring of Fluctuations in Carboxylesterase Activity in Diverse Biological Samples from a Single Organism.Analytical chemistry · 2024Article
- Cerium oxide nanoparticles-carrying human umbilical cord mesenchymal stem cells counteract oxidative damage and facilitate tendon regeneration.Journal of nanobiotechnology · 2023Article
- A near infrared fluorescent probe for rapid sensing of peroxynitrite in living cells and breast cancer mice.RSC advances · 2023Article
- Miniaturized Chemical Tags for Optical Imaging.Angewandte Chemie (International ed. in English) · 2022Review
- Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis.Topics in current chemistry (Cham) · 2022Review
- Horseradish peroxidase-triggered direct in situ fluorescent immunoassay platform for sensing cardiac troponin I and SARS-CoV-2 nucleocapsid protein in serum.Biosensors & bioelectronics · 2022Article
- Sequence-Activated Fluorescent Nanotheranostics for Real-Time Profiling Pancreatic Cancer.JACS Au · 2022Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two-photon fluorescence microscopy has become an indispensable technique for cellular imaging. Whereas most two-photon fluorescent probes rely on well-known fluorophores, here we report a new fluorophore for bioimaging, namely azulene. A chemodosimeter, comprising a boronate ester receptor motif conjugated to an appropriately substituted azulene, is shown to be an effective two-photon fluorescent probe for reactive oxygen species, showing good cell penetration, high selectivity for peroxynitrite, no cytotoxicity, and excellent photostability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.