ReviewHeart failure reviews2020
Left atrial strain in left ventricular diastolic dysfunction: have we finally found the missing piece of the puzzle?
Review in Heart failure reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Speckle tracking echocardiography and β-thalassemia major. A systematic review.Annals of hematology · 2024Pooled it
- The value of CMR-derived left atrial strain parameters in differential diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy.Quantitative imaging in medicine and surgery · 2026Article
- Left atrium strain in rheumatoid arthritis patients - a sub-study of the prospective Porto-RA cohort.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Observational
- A multimodal approach to early detection of anthracycline-induced cardiotoxicity: complementary roles of left ventricular global longitudinal strain, left atrial reservoir strain, and high-sensitivity troponin I.Journal of cardiovascular imaging · 2026Article
- Evaluation of Biventricular Diastolic Function in Preterm Infants in the First Week of Postnatal Life.Pediatric cardiology · 2026Observational
- Left atrial and ventricular impairment of asymptomatic pediatric myocarditis survivors: analysis by speckle tracking and exercise stress echocardiography.Quantitative imaging in medicine and surgery · 2026Article
- Proarrhythmogenic Echocardiographic Markers in Metabolic Syndrome: A Cross-Sectional Study.Life (Basel, Switzerland) · 2025Article
- Four-dimensional echocardiographic quantification of left atrial function in metabolic syndrome across different diastolic function states.BMC cardiovascular disorders · 2025Article
- Diagnostic tools of heart failure with preserved ejection fraction: Comparison of left atrial strain to the HFA-PEFF score.Global cardiology science & practice · 2025Article
- A First Diastolic Function Evaluation in the Personalized Exercise Prescription Program for Solid Organs Transplanted Subjects: Is Atrial Strain Useful?Journal of personalized medicine · 2025Article
- The power of the left atrioventricular coupling index in cardiovascular disease.Frontiers in cardiovascular medicine · 2025Review
- Relationship Between Left Atrial Strain and Atrial Fibrillation: The Role of Stress Echocardiography.Diagnostics (Basel, Switzerland) · 2024Review
- Left atrial strain in patients without cardiovascular disease: uncovering influencing and related factors.Cardiovascular ultrasound · 2024Article
- Interpreting Diastolic Dynamics and Evaluation through Echocardiography.Life (Basel, Switzerland) · 2024Review
- Endomyocardial involvement in asymptomatic Latin American migrants with eosinophilia related to helminth infection: A pilot study.PLoS neglected tropical diseases · 2024Observational
- Left Atrial Coupling Index Predicts Heart Failure in Patients with End Stage Renal Disease.Medicina (Kaunas, Lithuania) · 2024Article
- Left Atrial Strain for assessment of left ventricle diastolic dysfunction in acute coronary syndrome patients.La Tunisie medicale · 2024Article
- New perspectives in the echocardiographic hemodynamics multiparametric assessment of patients with heart failure.Heart failure reviews · 2024Review
- Potential Role of Left Atrial Strain to Predict Atrial Fibrillation Recurrence after Catheter Ablation Therapy: A Clinical and Systematic Review.Journal of cardiovascular development and disease · 2024Review
- MR 4D flow-derived left atrial acceleration factor for differentiating advanced left ventricular diastolic dysfunction.European radiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The noninvasive estimation of diastolic function with echocardiography as a surrogate of left ventricular filling pressure is considered an essential step in the clinical evaluation of patients with conditions predisposing to heart failure (HF). Latest algorithms for the assessment of diastolic dysfunction (DD) lay on several 2D standard parameters and describe a precise grading to quantify its severity. The persistence of a "gray zone" of values in which DD quantification is not possible, together with an epidemiological increase of conditions predisposing to heart failure with preserved ejection fraction (HFpEF), has led to the search and use of parameters with higher specificity and sensitivity: one of these is left atrial (LA) longitudinal strain in the frame of speckle tracking echocardiography (STE). LA anatomy and mechanics are crucial for preserving left ventricular (LV) function and asymptomatic condition of the patient. LA longitudinal strain is angle-independent, thus overcoming Doppler limitations, and provides reproducible measures of LA deformation. This review examines the latest evidences concerning the use of LA longitudinal strain in the assessment of diastolic function and HFpEF, with a particular focus on its role in standard echocardiographic algorithms or as a lone parameter to guide diagnosis and therapeutic management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.