ArticleJournal of cardiovascular translational research2020
Intermittent Occlusion of the Superior Vena Cava Reduces Cardiac Filling Pressures in Preclinical Models of Heart Failure.
Article in Journal of cardiovascular translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- Sustained Mechanical Occlusion of the Superior Vena Cava Safely Reduces Cardiac Filling Pressures in a Preclinical Model of Heart Failure.Journal of cardiovascular translational research · 2026Article
- Device-driven cyclic compression of the superior vena cava as a preload reduction strategy to improve cardiac function in heart failure: a pilot feasibility study.Scientific reports · 2026Article
- Right ventricular pressure-volume relations and effects of selective vena cava occlusion during cardiopulmonary resuscitation.PloS one · 2025Article
- Our initial experience of monitoring the autoregulation of cerebral blood flow during cardiopulmonary bypass.The journal of extra-corporeal technology · 2023Article
- Advances in novel devices for the treatment of heart failure.Heart failure reviews · 2023Review
- Targeting Preload in Heart Failure: Splanchnic Nerve Blockade and Beyond.Circulation. Heart failure · 2022Review
- A Glimpse Into the Future of Transcatheter Interventional Heart Failure Therapies.JACC. Basic to translational science · 2022Review
- First-in-Human Experience of Mechanical Preload Control in Patients With HFpEF During Exercise.JACC. Basic to translational science · 2021Article
- Turning Pressure Into Success: Preload Restriction in HFpEF?JACC. Basic to translational science · 2021Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
Congestion is a major determinant of clinical outcomes in heart failure (HF). We compared the acute hemodynamic effects of occlusion of the superior (SVC) versus the inferior vena cava (IVC) and tested a novel SVC occlusion system in swine models of HF. IVC occlusion acutely reduced left ventricular (LV) systolic and diastolic pressures, LV volumes, cardiac output (CO), and mean arterial pressure (MAP). SVC occlusion reduced LV diastolic pressure and volumes without affecting CO or MAP. The preCARDIA system is a balloon occlusion catheter and pump console which enables controlled delivery and removal of fluid into the occlusion balloon. At 6, 12, and 18 h, SVC therapy with the system provided a sustained reduction in cardiac filling pressures with stable CO and MAP. Intermittent SVC occlusion is a novel approach to reduce biventricular filling pressures in HF. The VENUS-HF trial will test the safety and feasibility of SVC therapy in HF.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.