Evidence map›Paper›PMID 31773453›Full record

ArticleGeroScience2020

Astrocyte senescence contributes to cognitive decline.

Tamas Csipo, Agnes Lipecz, Nicole M Ashpole, Priya Balasubramanian, Stefano Tarantini

Abstract readEditorial
In one paragraph

Article in GeroScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Review
  3. Hippocampal GFAP in aging: Associations with AD and LATE-NC pathologies and cognitive decline in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Review
  5. Article
  6. Aging, cellular senescence and Parkinson's disease.Journal of Parkinson's disease · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Cellular senescence in brain aging and cognitive decline.Frontiers in aging neuroscience · 2023
    Review
  15. Review
  16. Review
  17. Hepatic Encephalopathy and Melatonin.Antioxidants (Basel, Switzerland) · 2022
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tamas CsipoVascular Cognitive Impairment and Neurodegeneration Program, and Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Agnes LipeczVascular Cognitive Impairment and Neurodegeneration Program, and Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Nicole M AshpoleDepartment of BioMolecular Sciences, University of Mississippi School of Pharmacy, Oxford, MS, USA.
Priya BalasubramanianVascular Cognitive Impairment and Neurodegeneration Program, and Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Stefano TarantiniVascular Cognitive Impairment and Neurodegeneration Program, and Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. stefano-tarantini@ouhsc.edu.ORCID http://orcid.org/0000-0001-5627-1430

Funding

GEROSCIENCE TRAINING PROGRAM IN OKLAHOMAT32AG052363 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Benjamin Francis Miller, William Edmund Sonntag · 2017 to 2026
$3.6M
The Influence of IGF-1 on Astrocytic Regulation of Learning and MemoryR15AG059142 · NIA · UNIVERSITY OF MISSISSIPPI · PI ASHPOLE, NICOLE M · 2018 to 2018
$427k
NIA NIH HHS R15 AG059142NIA NIH HHS T32AG052363
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AstrocytesCognitive DysfunctionCellular SenescenceHumans

Identifiers

PMID31773453
PMCPMC7031460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.