Evidence map›Paper›PMID 31773320›Full record

ArticleEJNMMI research2019

Short-term discontinuation of vagal nerve stimulation alters

Ellen Boswijk, Renee Franssen, Guy H E J Vijgen, Roel Wierts, Jochem A J van der Pol, Alma M A Mingels, Erwin M J Cornips, Marian H J M Majoie, Wouter D van Marken Lichtenbelt, Felix M Mottaghy and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Ellen BoswijkDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0003-2613-515X
Renee FranssenDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.
Guy H E J VijgenSchool of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-6011-753X
Roel WiertsDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-9955-8754
Jochem A J van der PolDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-5698-3849
Alma M A MingelsDepartment of Clinical Chemistry, Maastricht University Medical Center (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-4648-5053
Erwin M J CornipsDepartment of Neurosurgery, Maastricht University Medical Center (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-5718-1696
Marian H J M MajoieDepartment of Research & Development, Epilepsy Center Kempenhaeghe, Sterkselseweg 65, 5591 VE, Heeze, The Netherlands.ORCID http://orcid.org/0000-0003-0579-8122
Wouter D van Marken LichtenbeltSchool of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-3316-2984
Felix M MottaghyDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-7212-6521
Joachim E WildbergerDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-4810-6854
Jan BuceriusDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands. jan.bucerius@med.uni-goettingen.de.ORCID http://orcid.org/0000-0002-8550-0682
Maastricht University · NLErasmus MC · NLMaastricht University Medical Centre · NL

Funding

FP7 Ideas: European Research Council HEALTH-F2-2011-278373Stichting De Weijerhorst Cardiovasculaire beeldvormingZonMw NWO-ZonMw 91209037
6 · The paper itself

Abstract

backgroundVagus nerve activation impacts inflammation. Therefore, we hypothesized that vagal nerve stimulation (VNS) influenced arterial wall inflammation as measured by

resultsTen patients with left-sided VNS for refractory epilepsy were studied during stimulation (VNS-on) and in the hours after stimulation was switched off (VNS-off). In nine patients,

conclusionsShort-term discontinuation of VNS did not show a consistent change in arterial wall

Indexed as

AtherosclerosisInflammationMetabolismPositron emission tomography (PET)Vagal nerve stimulation (VNS)

Identifiers

PMID31773320
PMCPMC6879675
OpenAlexW2990331729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.