ArticleLung2020
Lung Cancer in the Young.
Article in Lung, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Clinicopathological Characteristics, Molecular Findings, and Survival of Lung Cancer in Adults Aged <30 Years in China: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Inherited genetic risk factors in young-onset lung cancer.medRxiv : the preprint server for health sciences · 2026Article
- Phenotypic age acceleration and early-onset lung cancer: a case-control and prognostic cohort study involving multiple clinical centres with validation in the UK Biobank.EBioMedicine · 2026Article
- Clinical characteristics and survival in early-onset lung cancer: a multicenter cohort study.Frontiers in oncology · 2026Article
- Recent advances in hydrogel-based therapeutics for lung cancer.RSC advances · 2025Review
- Article
- The Clinical Characteristics, Treatment, and Prognosis of Lung Cancer in Young Patients in the New Era of Cancer Treatment: A Retrospective and Comprehensive Analysis.Current oncology (Toronto, Ont.) · 2025Article
- GMPS inhibits the proliferation and migration of non-small cell lung cancer via the regulation of the DNMT 1/SERPINB2 axis.Cellular oncology (Dordrecht, Netherlands) · 2025Article
- Article
- Young lung cancer: from diagnosis to survivorship.Frontiers in oncology · 2025Review
- Clinicopathological characteristics and prognosis of non-small cell lung cancer in Algeria: a single-center retrospective study.BMC cancer · 2024Article
- A Nomogram for Predicting Cancer-Specific Survival in Young Patients With Advanced Lung Cancer Based on Competing Risk Model.The clinical respiratory journal · 2024Article
- Factors that Influence the Need to Start Adaptive Radiotherapy.Journal of immunotherapy and precision oncology · 2024Article
- Actors influencing cancer-related fatigue and the construction of a risk prediction model in lung cancer patients.Frontiers in oncology · 2024Article
- Short- and long-term outcomes of robotic-assisted versus video-assisted thoracoscopic lobectomy in non-small cell lung cancer patients aged 35 years or younger: a real-world study with propensity score-matched analysis.Journal of cancer research and clinical oncology · 2023Article
- Driver and actionable mutations in younger patients with lung cancer - are we searching properly?Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2023Article
- The mediating role of self-efficacy in the relationship between social support and work withdrawal behavior: A cross-sectional study among young lung cancer survivors.Asia-Pacific journal of oncology nursing · 2023Article
- Sex-specificity in Surgical Stages of Lung Cancer in Young Adults.The open respiratory medicine journal · 2023Article
- Clinicopathological characteristics and prognosis of young patients aged ≤45 years old with non-small cell lung cancer.Open medicine (Warsaw, Poland) · 2023Article
- The clinico-pathological characteristics of surgically treated young women with NSCLC.Translational lung cancer research · 2022Article
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7 authors.
Funding
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Abstract
introductionMedian age at diagnosis of lung cancer is 70 years. Its presentation in patients 40 or younger is uncommon and it has been proposed that maybe it is a different disease due to its clinical characteristics and genetic makeup. There are a limited number of studies in this population and they report different clinic-pathological characteristics in comparison with older patients.
methodsWe described the incidence of lung cancer patients diagnosed at age 40 or younger at the Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima-Peru; from 2009 to 2017 and evaluated the characteristic of NSCLC. Epidemiologic and clinic-pathological data was collected from clinical files. Analysis was carried out using SPSSvs19 software.
resultsWe identified 3823 patients with lung cancer seen at INEN during the study period. Among these, 166 (4.3%) patients were 40 years or younger, and 137/166 (82.5%) were NSCLC. Median age at diagnosis was 36 years (range 14-40 years) and 59.1% of patients were female. A smoking history was present in 14.4% of patients. Frequent symptoms at diagnosis were cough (62.0%), chest pain (51.8%) and dyspnea (40.9%). Adenocarcinoma was the most common histological type (63.3%). Most patients had advanced disease at diagnosis (84.7%). The median overall survival was 8.2 months.
conclusionsThe proportion of young patients with lung cancer in our population is higher than that reported in the most recent literature. Lung cancer in the young is mostly sporadic, more frequent in women, usually adenocarcinoma type and it presents with advanced disease, resulting in a very poor survival.
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