Trial reportEuropean journal of nuclear medicine and molecular imaging2020
Textural features of hypoxia PET predict survival in head and neck cancer during chemoradiotherapy.
Trial report in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Radiomic model for differentiating parotid pleomorphic adenoma from parotid adenolymphoma based on MRI images.BMC medical imaging · 2021Trial
- Radiomics as a spatial context for treatment decision-making in head and neck cancer.British journal of cancer · 2026Review
- Review
- Predicting response to immunotherapy in oral squamous cell carcinoma via a CT-based radiomics model.BMC medical imaging · 2024Article
- A contrast-enhanced CT radiomics-based model to identify candidates for deintensified chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma patients.European radiology · 2024Article
- Performance of radiomics in the differential diagnosis of parotid tumors: a systematic review.Frontiers in oncology · 2024Review
- Methodological evaluation of original articles on radiomics and machine learning for outcome prediction based on positron emission tomography (PET).Nuklearmedizin. Nuclear medicine · 2023Review
- Current Role of Delta Radiomics in Head and Neck Oncology.International journal of molecular sciences · 2023Review
- The Role of Imaging Biomarkers to Guide Pharmacological Interventions Targeting Tumor Hypoxia.Frontiers in pharmacology · 2022Review
- Current Omics Trends in Personalised Head and Neck Cancer Chemoradiotherapy.Journal of personalized medicine · 2021Review
- Non-Homogeneous Tumor Growth and Its Implications for Radiotherapy: A Phenomenological Approach.Journal of personalized medicine · 2021Article
- The Biological Meaning of Radiomic Features.Radiology · 2021Review
- A Systematic Review of PET Textural Analysis and Radiomics in Cancer.Diagnostics (Basel, Switzerland) · 2021Review
- Application of radiomics and machine learning in head and neck cancers.International journal of biological sciences · 2021Review
- Evolution of the hypoxic compartment on sequential oxygen partial pressure maps during radiochemotherapy in advanced head and neck cancer.Physics and imaging in radiation oncology · 2021Article
- Comparison of patient stratification by computed tomography radiomics and hypoxia positron emission tomography in head-and-neck cancer radiotherapy.Physics and imaging in radiation oncology · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to investigate whether textural features of tumour hypoxia, assessed with serial [
methodsIn a preliminary evaluation of a prospective trial, tumour hypoxia was evaluated in 29 patients via serial FMISO-PET before and during CRT. All patients received an initial [
resultsWithin a median follow-up of 29.6 months (95% CI: 16.8-48.0 months), no first-order metrics predicted OS with a significant GS (all p > 0.05) on any FMISO-PET scan. Only u
conclusionsTextural features on FMISO-PET scans before CRT, in week 2 and, to a limited degree, the change of features during CRT, were able to identify head and neck squamous cell carcinoma patients with better OS, suggesting that a higher homogeneity of the degree of hypoxia in tumours could correlate with a better outcome after CRT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.