Evidence map›Paper›PMID 31773203›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2020

Comorbidities rather than age affect medium-term outcome in octogenarian patients after total knee arthroplasty.

Valerio Andreozzi, Fabio Conteduca, Raffaele Iorio, Enrico Di Stasio, Daniele Mazza, Piergiorgio Drogo, Alessandro Annibaldi, Andrea Ferretti

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Valerio AndreozziDepartment of Orthopaedics, Sapienza University of Rome, Sant'Andrea Hospital, Via Di Grottarossa 1035-1039, Rome, Italy.ORCID http://orcid.org/0000-0003-2291-2345
Fabio ConteducaDepartment of Orthopaedics, Sapienza University of Rome, Sant'Andrea Hospital, Via Di Grottarossa 1035-1039, Rome, Italy.
Raffaele IorioDepartment of Orthopaedics, Sapienza University of Rome, Sant'Andrea Hospital, Via Di Grottarossa 1035-1039, Rome, Italy.
Enrico Di StasioIstituto Di Biochimica E Biochimica Clinica, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168, Rome, Italy. enrico.distasio@unicatt.it.ORCID http://orcid.org/0000-0003-1047-4261
Daniele MazzaDepartment of Orthopaedics, Sapienza University of Rome, Sant'Andrea Hospital, Via Di Grottarossa 1035-1039, Rome, Italy.
Piergiorgio DrogoDepartment of Orthopaedics, Sapienza University of Rome, Sant'Andrea Hospital, Via Di Grottarossa 1035-1039, Rome, Italy.
Alessandro AnnibaldiDepartment of Orthopaedics, Sapienza University of Rome, Sant'Andrea Hospital, Via Di Grottarossa 1035-1039, Rome, Italy.
Andrea FerrettiDepartment of Orthopaedics, Sapienza University of Rome, Sant'Andrea Hospital, Via Di Grottarossa 1035-1039, Rome, Italy.
Sapienza University of Rome · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAs the population ages, it is important to determine whether total knee arthroplasties (TKA)s are safe and beneficial in the octogenarian population. The aims of the present study were: (1) to assess the effect of comorbidities and age on the incidence of postoperative complications following TKA and (2) to evaluate the mid-term outcome of octogenarian patients.

methodsA retrospective matched-paired analysis by gender, BMI and duration of follow-up was conducted on 206 patients older than 80 years and younger than 75 years between 2009 and 2016, undergoing primary TKA. The mean follow-up was 5 years. Outcome measures including Oxford Knee Score (OKS), Knee Society Score (KSS), Knee Society Function Score (KSFS), postoperative complications, length of stay (LOS) and survivorship were analysed. The association between complications and comorbidities was assessed using multivariable logistic regression after adjusting for age, Deyo-Charlson Comorbidity Index (D-CCI) and the American Society of Anesthesiologist's (ASA) physical status classification.

resultsIn the multivariable models, D-CCI class is an independent predictor for postoperative cardiac complications, delirium and transfusion rate (OR ranging from 1.2 to 69.5 in respect to D-CCI reference class 0). Being ≥ 80 years old was associated with an increased risk of transfusion (OR 3.4; 95% CI 1.7-6.8) and 1.7-day increase in LOS (p < 0.001). Both groups showed significant improvement in postoperative knee scores following TKA.

conclusionOctogenarians experienced good clinical results when compared to their younger counterparts. Comorbidities, rather than age itself, are responsible for the increase in postoperative morbidity. Preoperative risk assessment has to be optimized in order to reduce complications.

Indexed as

ComorbidityAgedAged, 80 and overAge FactorsArthroplasty, Replacement, KneeBlood TransfusionFemaleHumansIncidenceItalyKnee JointLength of StayMaleOutcome Assessment, Health CarePostoperative ComplicationsPostoperative PeriodComorbidityComplicationElderlyOctogenarianTotal knee arthroplastyTotal knee replacement

Identifiers

PMID31773203
OpenAlexW2990082442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.