Evidence map›Paper›PMID 31773057›Full record

ArticleTransplantation direct2019

Epidemiology and Comorbidity Burden of Organ Donor Referrals in Australia: Cohort Study 2010-2015.

Imogen K Thomson, Brenda M Rosales, Patrick J Kelly, Kate Wyburn, Karen M J Waller, Daniel Hirsch, Michael J O'Leary, Angela C Webster

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Imogen K ThomsonSchool of Public Health, Faculty of Health Sciences and Medicine, University of Sydney, Camperdown, NSW, Australia.
Brenda M RosalesSchool of Public Health, Faculty of Health Sciences and Medicine, University of Sydney, Camperdown, NSW, Australia.
Patrick J KellySchool of Public Health, Faculty of Health Sciences and Medicine, University of Sydney, Camperdown, NSW, Australia.
Kate WyburnSchool of Public Health, Faculty of Health Sciences and Medicine, University of Sydney, Camperdown, NSW, Australia.
Karen M J WallerSchool of Public Health, Faculty of Health Sciences and Medicine, University of Sydney, Camperdown, NSW, Australia.
Daniel HirschSchool of Public Health, Faculty of Health Sciences and Medicine, University of Sydney, Camperdown, NSW, Australia.
Michael J O'LearyIntensive Care Unit, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Angela C WebsterSchool of Public Health, Faculty of Health Sciences and Medicine, University of Sydney, Camperdown, NSW, Australia.
Royal Prince Alfred Hospital · AUWestmead Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing organ donation rates in Australia have been exceeded by a rise in potential donor referrals not proceeding to donate. Referral evaluation is resource-intensive. We sought to characterize organ donor referrals in New South Wales, Australia, and identify predictors of referrals not proceeding to donation.

methodsWe performed a cohort study of NSW Organ and Tissue Donation Service logs 2010-2015, describing the prevalence and impact of comorbidities on referral outcome. Logistic regression was used to identify comorbidities influencing outcome and predict probability of donation.

resultsOf 2977 referrals, 669 (22%) donated and 2308 (78%) did not. Despite increasing donation rates, the proportion proceeding to donate declined 2010-2015. Among referrals, the prevalence of all comorbidities except cerebrovascular disease increased and was higher among nondonors. History of cardiac disease, ≥65 years of age, chronic kidney or liver disease, malignancy, and absence of cerebrovascular disease were all significantly (

conclusionsComorbidity burden among donor referrals is increasing. The presence of particular comorbidities may significantly impact referral outcome. A better understanding of referral characteristics associated with non donation may improve the efficiency of the referral process in the context of encouraging routine referrals.

Identifiers

PMID31773057
PMCPMC6831119
OpenAlexW2980384490

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.