Evidence map›Paper›PMID 31772912›Full record

ArticleCurrent tropical medicine reports2019

Immunization Strategies for the Control of Histoplasmosis.

Maxwell T Roth, Daniel Zamith-Miranda, Joshua D Nosanchuk

Open access · greenAbstract read
In one paragraph

Article in Current tropical medicine reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Comparative Genomics ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  3. Review
  4. Subcutaneous Mycoses in Travelers.Current tropical medicine reports · 2020
    Article
  5. Immunoproteomics Reveals Pathogen's Antigens Involved inFrontiers in cellular and infection microbiology · 2020
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maxwell T RothDepartment of Medicine (Division of Infectious Diseases) and Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Daniel Zamith-MirandaDepartment of Medicine (Division of Infectious Diseases) and Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0001-7532-2432
Joshua D NosanchukDepartment of Medicine (Division of Infectious Diseases) and Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0001-9905-5754
Albert Einstein College of Medicine · US

Funding

Antibody differentially alters Histoplasma extracellular vesiclesR21AI124797 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI NOSANCHUK, JOSHUA D · 2016 to 2017
$538k
NIAID NIH HHS R21 AI124797
6 · The paper itself

Abstract

Histoplasmosis is an infection caused by the dimorphic fungus PURPOSE OF REVIEW: This review will detail some of the major developments in potential vaccines against histoplasmosis, with particular emphasis on those that could be used to immunize immunocompromised hosts. Additionally, this review will highlight some non-traditional vaccine-like ideas for the prevention of diverse mycoses. RECENT

findingsHistorically, immunization strategies against histoplasmosis have largely focused on identifying immunogenic proteins that confer protection in animal models. More recently, novel active, therapeutic, and immunomodulatory strategies have been explored as potential alternatives for those with various immune-deficiencies. SUMMARY: The studies summarized in this review demonstrate that more research is needed to clarify the immunobiology, clinical role and efficacy of each candidate vaccine in the ever-expanding potential armamentarium against histoplasmosis.

Indexed as

antibodiesH. capsulatumhistoplasmosisimmune-therapyT cellsvaccine

Identifiers

PMID31772912
PMCPMC6879175
OpenAlexW2923602217

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.