Evidence map›Paper›PMID 31772701›Full record

ArticleOxidative medicine and cellular longevity2019

Resistin in Human Seminal Plasma: Relationship with Lipid Peroxidation, CAT Activity, GSH/GSSG Ratio, and Semen Parameters.

Elena Moretti, Lucia Micheli, Daria Noto, Anna Ida Fiaschi, Andrea Menchiari, Daniela Cerretani

Abstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elena MorettiDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID https://orcid.org/0000-0002-9467-0501
Lucia MicheliDepartment of Medical and Surgical Sciences and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID https://orcid.org/0000-0002-0306-9308
Daria NotoDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID https://orcid.org/0000-0002-1571-9056
Anna Ida FiaschiDepartment of Medical and Surgical Sciences and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID https://orcid.org/0000-0001-8017-4198
Andrea MenchiariDepartment of Business and Law, University of Siena, 53100 Siena, Italy.
Daniela CerretaniDepartment of Medical and Surgical Sciences and Neurosciences, University of Siena, 53100 Siena, Italy.ORCID https://orcid.org/0000-0001-9498-1644

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistin is an adipokine involved in inflammation and able to induce the expression of other proinflammatory cytokines. It is known that, in human semen, resistin is correlated with inflammatory cytokines and sperm quality. The aim of this prospective study was to explore the potential relationship between resistin, lipid peroxidation (LPO), catalase (CAT) activity, and reduced and oxidized glutathione (GSH/GSSG) ratio in semen samples of infertile patients with leukocytospermia (no. 19), infertile patients with varicocele (no. 17), and fertile men (no. 17). Semen analysis was performed following the WHO guidelines, and sperm apoptosis and necrosis were evaluated with annexin V/propidium iodide assay. Seminal plasma samples were used to determine resistin levels by an immunological method, MDA concentration by a HPLC analysis with UV detection, GSH/GSSG ratio by an enzymatic method, CAT activity by a spectrophotometric method. The results showed that, in both groups of infertile patients, semen parameters were significantly reduced (

Indexed as

AdultGlutathione DisulfideHumansLipid PeroxidationMaleResistinSemenGlutathione DisulfideResistin

Identifiers

PMID31772701
PMCPMC6854241

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.