Evidence map›Paper›PMID 31772691›Full record

ArticleDisease markers2019

The Utility of Comprehensive Metabolic Panel Tests for the Prediction of Bronchopulmonary Dysplasia in Extremely Premature Infants.

Xueyu Chen, Binchun Lin, Xiaoyun Xiong, Panpan Sun, Yanqing Kong, Chuanzhong Yang

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xueyu ChenDepartment of Neonatology, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Hongli Rd, 2004, 518507 Shenzhen, China.ORCID https://orcid.org/0000-0002-7066-0501
Binchun LinDepartment of Neonatology, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Hongli Rd, 2004, 518507 Shenzhen, China.
Xiaoyun XiongDepartment of Neonatology, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Hongli Rd, 2004, 518507 Shenzhen, China.
Panpan SunDepartment of Neonatology, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Hongli Rd, 2004, 518507 Shenzhen, China.ORCID https://orcid.org/0000-0002-2848-8752
Yanqing KongDepartment of Pathology, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Hongli Rd, 2004, 518507 Shenzhen, China.
Chuanzhong YangDepartment of Neonatology, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Hongli Rd, 2004, 518507 Shenzhen, China.ORCID https://orcid.org/0000-0002-5093-0308
Shenzhen Maternity and Child Healthcare Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComprehensive metabolic panel tests (CMP) are routinely performed in extremely premature infants within the first days of life. The association between the parameters of first postnatal CMP and the risk of bronchopulmonary dysplasia (BPD) remains elusive.

methodsA retrospective analysis was performed to evaluate the correlation between the parameters of first postnatal CMP and the risk of BPD in a cohort of extremely premature infants (born with a gestational age less than 28 weeks or a birth weight less than 1000 grams) at the neonatal intensive care unit, Shenzhen Maternity and Child Healthcare Hospital, from January 2016 to October 2018. A multivariant regression model was built to assess the association of the first postnatal CMP with the development of BPD.

resultsA total of 256 extremely premature infants were included in this study. BPD developed in 76 (29.7%) infants. The first CMP in these infants was performed at 5 to 8 days after birth. The levels of blood urea nitrogen (BUN) and magnesium were significantly higher in infants with BPD compared to infants with no BPD (10.2 versus 7.5 mmol/L,

conclusionOur findings indicate that a higher postnatal BUN level (>8.18 mmol/L) may be a predictor for the development of BPD in extremely premature infants.

Indexed as

Alkaline PhosphataseBiomarkersBirth WeightBlood Chemical AnalysisBlood ProteinsBlood Urea NitrogenBronchopulmonary DysplasiaCase-Control StudiesCohort StudiesFemaleGestational AgeHumansInfant, Extremely PrematureInfant, NewbornMagnesiumMaleAlkaline PhosphataseBiomarkersBlood ProteinsMagnesium

Identifiers

PMID31772691
PMCPMC6854975
OpenAlexW2980446786

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.