Evidence map›Paper›PMID 31772685›Full record

ArticleDisease markers2019

Plasma Betatrophin Levels and Carotid Atherosclerosis.

Hanako Niki, Yoshimi Kishimoto, Emi Saita, Reiko Ohmori, Kazuo Kondo, Yukihiko Momiyama

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hanako NikiDepartment of Cardiology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Yoshimi KishimotoEndowed Research Department "Food for Health", Ochanomizu University, Tokyo, Japan.
Emi SaitaEndowed Research Department "Food for Health", Ochanomizu University, Tokyo, Japan.
Reiko OhmoriFaculty of Regional Design, Utsunomiya University, Tochigi, Japan.
Kazuo KondoEndowed Research Department "Food for Health", Ochanomizu University, Tokyo, Japan.
Yukihiko MomiyamaDepartment of Cardiology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.ORCID https://orcid.org/0000-0002-7710-1446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsBetatrophin is a recently identified circulating adipokine that may affect lipid and glucose metabolism. However, the association between plasma betatrophin levels and carotid atherosclerosis has not been elucidated.

methodsWe investigated plasma betatrophin levels in 153 subjects undergoing carotid ultrasonography. The severity of plaque was evaluated as plaque score.

resultsOf the 153 subjects, plaque was found in 63 (41%). Plasma betatrophin levels were higher in 63 subjects with plaque than in 90 without plaque (median 906 vs. 729 pg/mL,

conclusionsPlasma betatrophin levels were found to be high in subjects with carotid plaque and to be associated with the severity of plaque. Betatrophin may play a role in the progression of carotid atherosclerosis.

Indexed as

AdultAgedAged, 80 and overAngiopoietin-Like Protein 8Angiopoietin-like ProteinsBiomarkersCarotid Artery DiseasesC-Reactive ProteinFemaleHumansMaleMiddle AgedMultivariate AnalysisPeptide HormonesPlaque, AtheroscleroticTriglyceridesAngiopoietin-Like Protein 8Angiopoietin-like ProteinsANGPTL8 protein, humanBiomarkersC-Reactive ProteinPeptide HormonesTriglycerides

Identifiers

PMID31772685
PMCPMC6854246

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.