Evidence map›Paper›PMID 31772635›Full record

ArticleExperimental and therapeutic medicine2019

Chrysophanol alleviates myocardial injury in diabetic

Peng Xue, Jing Zhao, Aibin Zheng, Lin Li, Huaqin Chen, Wenjuan Tu, Ning Zhang, Zhangbin Yu, Qiuwei Wang, Meng Gu

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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  13. Chrysophanol Protects Against Acute Heart Failure by Inhibiting JNK1/2 Pathway in Rats.Medical science monitor : international medical journal of experimental and clinical research · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Peng XueDepartment of Pediatrics, Changzhou Children's Hospital of Nantong Medical University, Changzhou, Jiangsu 213003, P.R. China.
Jing ZhaoDepartment of Pediatrics, Changzhou Children's Hospital of Nantong Medical University, Changzhou, Jiangsu 213003, P.R. China.
Aibin ZhengDepartment of Pediatrics, Changzhou Children's Hospital of Nantong Medical University, Changzhou, Jiangsu 213003, P.R. China.
Lin LiDepartment of Pediatrics, Changzhou Children's Hospital of Nantong Medical University, Changzhou, Jiangsu 213003, P.R. China.
Huaqin ChenDepartment of Pediatrics, Changzhou Children's Hospital of Nantong Medical University, Changzhou, Jiangsu 213003, P.R. China.
Wenjuan TuDepartment of Pediatrics, Changzhou Children's Hospital of Nantong Medical University, Changzhou, Jiangsu 213003, P.R. China.
Ning ZhangDepartment of Pediatrics, Changzhou Children's Hospital of Nantong Medical University, Changzhou, Jiangsu 213003, P.R. China.
Zhangbin YuDepartment of Pediatrics, Nanjing Maternity and Child Health Care Hospital of Nanjing Medical University, Nangjing, Jiangsu 210004, P.R. China.
Qiuwei WangDepartment of Pediatrics, Changzhou Children's Hospital of Nantong Medical University, Changzhou, Jiangsu 213003, P.R. China.
Meng GuDepartment of Pediatrics, Changzhou Children's Hospital of Nantong Medical University, Changzhou, Jiangsu 213003, P.R. China.
Hangzhou Children's Hospital · CNNanjing Maternity and Child Health Care Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial injury induced by diabetes has become an increasing health problem. Chrysophanol (CHR) has been widely studied as a potential treatment for many diseases due to its anti-inflammatory effects, but has not been investigated in regard to diabetes-induced myocardial injury. The present study evaluated the myocardial protective effects of CHR in C57BL/KsJ-

Indexed as

chrysophanolhigh mobility group box 1/NF-κBinflammationmyocardial injurysilent information regulator l

Identifiers

PMID31772635
PMCPMC6862128
OpenAlexW2980029828

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.