Evidence map›Paper›PMID 31772615›Full record

Trial reportCardiovascular therapeutics2019

Comparison of the Effect of Fimasartan versus Valsartan on Blood Pressure Variability in Acute Ischemic Stroke: A Double-Blind Randomized Trial.

Dong Hoon Shin, Soohwa Song, Yeong Bae Lee

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Cardiovascular therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dong Hoon ShinDepartment of Neurology, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.ORCID 0000-0002-1103-1983
Soohwa SongDepartment of Biomedical Engineering, Gachon University of Medicine and Science, Incheon, Republic of Korea.
Yeong Bae LeeDepartment of Neurology, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.ORCID 0000-0001-5952-1423
Gachon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Higher blood pressure variability (BPV) is associated with poor functional outcome and mortality in acute stroke. This randomized controlled trial was conducted to compare the effect on BPV between fimasartan and valsartan (Boryung Pharmaceutical Co., Ltd., Seoul, Republic of Korea) in patients with acute ischemic stroke. Eighty patients were randomly assigned to receive either valsartan or fimasartan after 7 days of acute ischemic stroke onset, for duration of 8 weeks. Of them, 62 patients completed the study [valsartan (n=31), fimasartan (n=31)]. We measured BP for 24 hours using ambulatory BP monitoring device before and after 8 weeks of starting BP medication. We calculated several indexes such as standard deviation (SD), weighted 24-hour BP with SD (wSD), coefficient of variation (CV), and average real variability (ARV) to assess BPV and to compare indexes of BPV between 2 drugs. SD values of systolic BP in daytime, nighttime, and 24 h period (15.55±4.02 versus 20.55±8.77,

Indexed as

Angiotensin II Type 1 Receptor BlockersBiphenyl CompoundsBlood PressureBrain IschemiaDouble-Blind MethodHumansProspective StudiesPyrimidinesRepublic of KoreaStrokeTetrazolesTime FactorsTreatment OutcomeValsartanAngiotensin II Type 1 Receptor BlockersBiphenyl CompoundsfimasartanPyrimidinesTetrazolesValsartan

Identifiers

PMID31772615
PMCPMC6739756
OpenAlexW2947722117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.