ArticleJournal of interventional cardiology2019
Impact of Hydrostatic Pressure Variations Caused by Height Differences in Supine and Prone Positions on Fractional Flow Reserve Values in the Coronary Circulation.
Article in Journal of interventional cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diagnostic Performance of Non-Hyperemic Pressure Ratios Versus Fractional Flow Reserve Stratified by Coronary Artery: A Systematic Review and Meta-Analysis of Individual Patient Data.Journal of the American Heart Association · 2026Pooled it
- Angiography-based coronary microvascular assessment with and without intracoronary pressure measurements: a systematic review.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Pooled it
- Differential stress-induced ischemic electrocardiographic changes in acute versus stable coronary syndromes with severely reduced fractional flow reserve (≤0.60).International journal of cardiology. Heart & vasculature · 2026Article
- Vessel-Specific Differences in Fractional Flow Reserve Among Intermediate Coronary Lesions.Journal of clinical medicine · 2026Article
- Coronary Physiology Across the Whole Spectrum of Ischemic Heart Disease.Journal of clinical medicine · 2026Review
- Murray law-based quantitative flow ratio versus invasive fractional flow reserve in the left anterior descending coronary artery: impact of hydrostatic pressure correction and clinical implications.Frontiers in cardiovascular medicine · 2026Article
- Impact of Epicardial plaQUe Composition and geomeTry on Coronary hEmodynamics and Flow in Patients With Coronary Artery Disease (iEquate).Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Observational
- A Vessel-Specific Analysis of Deferred Lesions Using the Instantaneous Wave-Free Ratio and Fractional Flow Reserve.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- The Impact of Hydrostatic Pressure on Fractional Flow Reserve in Saphenous Vein Grafts.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Article
- Clinical Implications of Fractional Flow Reserve Measured Immediately After Percutaneous Coronary Intervention.Cardiovascular drugs and therapy · 2024Article
- The Effect of Hydrostatic Pressure on Coronary Flow and Pressure-Based Indices of Coronary Stenosis Severity.Journal of clinical medicine · 2024Article
- The pressure-derived microvascular resistance reserve and its correlation to Doppler MRR measurement-a proof of concept study.Frontiers in cardiovascular medicine · 2024Article
- Safety and Feasibility Using a Fluid-Filled Wire to Avoid Hydrostatic Errors in Physiological Intracoronary Measurements.Cardiology research and practice · 2024Article
- Article
- Pressure- and 3D-Derived Coronary Flow Reserve with Hydrostatic Pressure Correction: Comparison with Intracoronary Doppler Measurements.Journal of personalized medicine · 2022Article
- Coronary Microvascular Vasodilatory Function: Related Clinical Features and Differences According to the Different Coronary Arteries and Types of Coronary Spasm.Journal of clinical medicine · 2021Article
- Influence of different physiological hemodynamics on fractional flow reserve values in the left coronary artery and right coronary artery.Heart and vessels · 2021Article
- The impact of hydrostatic pressure on the result of physiological measurements in various coronary segments.The international journal of cardiovascular imaging · 2021Article
- Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine the influence of hydrostatic pressure on fractional flow reserve (FFR) in vivo.
backgroundSystematic differences in FFR values have been observed previously in the left anterior descending artery (LAD), left circumflex artery (LCX), and right coronary artery (RCA). It has been suggested that as the hydrostatic pressure variations caused by the height differences between the catheter tip (mean aortic pressure (Pa)) and pressure-wire sensor (mean distal intracoronary pressure (Pd)) are small, intracoronary pressure need not be corrected.
methodsResting Pd/Pa and FFR values in 23 patients (27 lesions) were measured and compared in supine and prone positions. These values were corrected by hydrostatic pressure influenced by height levels and compared. Height differences between Pa and Pd were calculated using coronary computed tomography angiographies.
resultsIn LAD, resting Pd/Pa and FFR values were significantly higher in the prone position than in the supine position (0.97 ± 0.05 vs 0.89 ± 0.04,
conclusionsHydrostatic pressure variations due to height levels influence intracoronary pressure measurements and largely affect resting Pd/Pa and FFR, which might have caused systematic differences in FFR values between the anterior and posterior coronary territories.
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