Evidence map›Paper›PMID 31772505›Full record

ReviewMediators of inflammation2019

Autoantibodies as Diagnostic Markers and Mediator of Joint Inflammation in Arthritis.

Qinghua Fang, Jiaxin Ou, Kutty Selva Nandakumar

Open access · goldAbstract readReview
In one paragraph

Review in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Ozoralizumab, a trivalent anti-TNFα NANOBODYFrontiers in immunology · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Correlation genotype-phenotype:The Pan African medical journal · 2022
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Qinghua FangSchool of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
Jiaxin OuSchool of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
Kutty Selva NandakumarSchool of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0001-7790-8197
Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis is a systemic, polygenic, and multifactorial syndrome characterized by erosive polyarthritis, damage to joint architecture, and presence of autoantibodies against several self-structures in the serum and synovial fluid. These autoantibodies (anticitrullinated protein/peptide antibodies (ACPAs), rheumatoid factors (RF), anticollagen type II antibodies, antiglucose-6 phosphate isomerase antibodies, anticarbamylated protein antibodies, and antiacetylated protein antibodies) have different characteristics, diagnostic/prognostic value, and pathological significance in RA patients. Some of these antibodies are present in the patients' serum several years before the onset of clinical disease. Various genetic and environmental factors are associated with autoantibody production against different autoantigenic targets. Both the activating and inhibitory Fc

Indexed as

Arthritis, RheumatoidAutoantibodiesFemaleHumansInflammationMalePeptides, CyclicRheumatoid FactorAutoantibodiescyclic citrullinated peptidePeptides, CyclicRheumatoid Factor

Identifiers

PMID31772505
PMCPMC6854956
OpenAlexW2981601242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.