Evidence map›Paper›PMID 31772465›Full record

ArticleContemporary clinical dentistry

Transforming Growth Factor-β1 and Runt-related Transcription Factor 2 as Markers of Osteogenesis in Stem Cells from Human Exfoliated Deciduous Teeth Enriched Bone Grafting.

Chiquita Prahasanti, Noer Ulfah, Ivan Indra Kusuma, Nur Hayati, Diah Savitri Ernawati, Agung Krismariono, Taufan Bramantoro

Open access · goldAbstract read
In one paragraph

Article in Contemporary clinical dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chiquita PrahasantiDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Noer UlfahDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Ivan Indra KusumaDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Nur HayatiDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Diah Savitri ErnawatiDepartment of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Agung KrismarionoDepartment of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Taufan BramantoroDepartment of Dental Public Health, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
Airlangga University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStem cells from human exfoliated deciduous teeth (SHED) are one source of adult stem cells which can proliferate and differentiate into many types of tissues than any other stem cells. SHED represent potential stem cells for therapeutic therapy and tissue engineering.

aimsThe aim of this study was to compare the expression of transforming growth factor-β1 (TGF-β1) and runt-related transcription factor 2 (RUNX2) in hydroxyapatite (HA) scaffold with SHED. SUBJECTS AND

methodsEight experimental animals were divided into two groups. The first group was transplanted with HA and the second with HA and SHED. The expression of TGF-β1 and RUNX2 was seen 21 days later by means of immunohistochemical analysis. STATISTICAL ANALYSIS USED: Data were analyzed using an independent

resultsThe analysis results of an independent

conclusionsExpression of TGF-β1 and RUNX2 occurs after the application of HA with SHED, while TGF-β1 and RUNX2 expression in the HA with SHED group was significantly higher than in the group without SHED.

Indexed as

Hydroxyapatiterunt-related transcription factor 2stem cells from human exfoliated deciduous teethtransforming growth factor-β1

Identifiers

PMID31772465
PMCPMC6868629
OpenAlexW2988815930

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.