ArticleScientific reports2019
Oxidative status and metabolic profile in a long-lived bird preparing for extreme endurance migration.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 70 citations in OpenAlex.
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- Metabolomic profiles reveal physiological transitions required for long-distance avian migration.Scientific reports · 2026Article
- To Migrate or not to Migrate? Exploring the Genomic Basis of Partial Migratory Behavior in Bats.Genome biology and evolution · 2025Article
- What Factors Shape the Flyability in Bats?-The Perspective from Bat's Wing Development.Biology · 2025Review
- Flexibility in the face of climate change? A rapid and dramatic shift towards later spring migration in Hudsonian godwits (Proceedings. Biological sciences · 2025Article
- Seabirds in crisis: Plastic ingestion induces proteomic signatures of multiorgan failure and neurodegeneration.Science advances · 2025Article
- Magnetic sense-dependent probabilistic decision-making in humans.Frontiers in neuroscience · 2025Article
- Energetics and Oxidative Status: Seasonal Variation in Blood Oxidative Stress Metrics in Four Species of Small Birds from a Cold Winter Climate.Integrative organismal biology (Oxford, England) · 2025Article
- Species-specific physiological status in seabirds: insights from integrating oxidative stress measurements and biologging.Frontiers in physiology · 2025Article
- Mitochondrial remodelling supports migration in white-crowned sparrows (Proceedings. Biological sciences · 2024Article
- Inter-organ differences in redox imbalance and apoptosis depict metabolic resilience in migratory redheaded buntings.Scientific reports · 2024Article
- Flexibility underlies differences in mitochondrial respiratory performance between migratory and non-migratory White-crowned Sparrows (Zonotrichia leucophrys).Scientific reports · 2024Article
- Assessment of avian health status: suitability and constraints of the Zoetis VetScan VS2 blood analyser for ecological and evolutionary studies.Biology open · 2023Article
- Long-duration wind tunnel flights reveal exponential declines in protein catabolism over time in short- and long-distance migratory warblers.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Geographic variation in the altitudinal migration patterns, body size, oxidative status and exploratory behavior in a neotropical bird.Ecology and evolution · 2023Article
- The oxidative balance and stopover departure decisions in a medium- and a long-distance migrant.Movement ecology · 2023Article
- Utilizing NMR fecal metabolomics as a novel technique for detecting the physiological effects of food shortages in waterfowl.Frontiers in physiology · 2023Article
- Mitochondrial oxidative phosphorylation response overrides glucocorticoid-induced stress in a reptile.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2022Article
- Article
- Estimation of Redox Status in Military Pilots during Hypoxic Flight-Simulation Conditions-A Pilot Study.Antioxidants (Basel, Switzerland) · 2022Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The high metabolic activity associated with endurance flights and intense fuelling of migrant birds may produce large quantities of reactive oxygen species, which cause oxidative damage. Yet it remains unknown how long-lived birds prepare for oxidative challenges prior to extreme flights. We combined blood measurements of oxidative status and enzyme and fat metabolism in Hudsonian godwits (Limosa haemastica, a long-lived shorebird) before they embarked on non-stop flights longer than 10,000 km during their northbound migrations. We found that godwits increased total antioxidant capacity (TAC) and reduced oxidative damage (TBARS) as the pre-migratory season progressed, despite higher basal metabolic rates before departure. Elevations in plasma β-hydroxybutyrate and uric acid suggest that lipid and protein breakdown supports energetic requirements prior to migration. Significant associations between blood mitochondrial cytochrome-c oxidase and plasma TAC (negative) and TBARS (positive) during winter indicate that greater enzyme activity can result in greater oxidative damage and antioxidant responses. However enzyme activity remained unchanged between winter and premigratory stages, so birds may be unable to adjust metabolic enzyme activity in anticipation of future demands. These results indicate that godwits enhance their oxidative status during migratory preparation, which might represent an adaptation to diminish the physiological costs of long-distance migration.
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