ArticleScientific reports2019
Proteome characterization of used nesting material and potential protein sources from group housed male mice, Mus musculus.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 22 citations in OpenAlex.
- Impact of Bedding Volume on Cage Microclimate and Behavior in 129SV and Desmin-Knockout (Des-/-) Mice.Animals : an open access journal from MDPI · 2026Article
- Extracellular matrix deposition precedes muscle-tendon integration during murine forelimb morphogenesis.Communications biology · 2025Article
- Identification of Plasma Free Fatty Acid Carrier Proteins in Mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- A cell fractionation and quantitative proteomics pipeline to enable functional analyses of cotton fiber development.The Plant journal : for cell and molecular biology · 2025Article
- Effects of Nesting Material and Housing Parameters on Feed Wastage Behavior in Female Swiss Webster Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2024Article
- Proteomic analysis of murine kidney proximal tubule sub-segment derived cell lines reveals preferences in mitochondrial pathway activity.Journal of proteomics · 2023Article
- Essential amino acids in the Plant-Conserved and Class-Specific Regions of cellulose synthases.Plant physiology · 2023Article
- Identification of Rodent Husbandry Refinement Opportunities through Benchmarking and Collaboration.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Article
- Furosemide-induced systemic dehydration alters the proteome of rabbit vocal folds.Journal of proteomics · 2022Article
- Assessing the effect of compounds from plantar foot sweat, nesting material, and urine on social behavior in male mice, Mus musculus.PloS one · 2022Article
- Mammalian derived lipocalin and secretoglobin respiratory allergens strongly bind ligands with potentially immune modulating properties.Frontiers in allergy · 2022Article
- Article
- Major urinary protein excreted in rodent hindpaw sweat.Journal of anatomy · 2021Article
- Impact of Exposure to Chronic Light-Dark Phase Shifting Circadian Rhythm Disruption on Muscle Proteome in Periparturient Dairy Cows.Proteomes · 2021Article
- Who's the Boss? Assessing Convergent Validity of Aggression Based Dominance Measures in Male Laboratory Mice,Frontiers in veterinary science · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laboratory mice (Mus musculus) communicate a variety of social messages through olfactory cues and it is often speculated that these cues are preserved in nesting material. Based on these speculations, a growing number of husbandry recommendations support preserving used nests at cage cleaning to maintain familiar odors in the new cage. However, the content of used nesting material has never been chemically analyzed. Here we present the first comprehensive proteome profile of used nesting material. Nests from cages of group housed male mice contain a variety of proteins that primarily originate from saliva, plantar sweat, and urine sources. Most notably, a large proportion of proteins found in used nesting material belong to major urinary protein ("MUP") and odorant binding protein ("OBP") families. Both protein families send messages about individual identity and bind volatile compounds that further contribute to identity cues. Overall, this data supports current recommendations to preserve used nesting material at cage cleaning to maintain odor familiarity.
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