Evidence map›Paper›PMID 31772048›Full record

ArticlemBio2019

Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice.

Clare M Smith, Megan K Proulx, Rocky Lai, Michael C Kiritsy, Timothy A Bell, Pablo Hock, Fernando Pardo-Manuel de Villena, Martin T Ferris, Richard E Baker, Samuel M Behar and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. A New Mouse Model for Ozone Health Effects Research.Environmental health perspectives · 2026
    Article
  3. Review
  4. Review
  5. Journal of bacteriology · 2026
    Review
  6. CD8+ lymphocytes in immunity against tuberculosis.Journal of immunology (Baltimore, Md. : 1950) · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. The chosen few:Frontiers in immunology · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Clare M Smith *Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0003-2601-0955
Megan K Proulx *Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0002-9524-8302
Rocky Lai *Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0002-3394-3086
Michael C KiritsyDepartment of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0001-8364-8088
Timothy A BellDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-9546-6334
Pablo HockDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Fernando Pardo-Manuel de VillenaDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-5738-5795
Martin T FerrisDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0003-1241-6268
Richard E BakerDepartment of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Samuel M BeharDepartment of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0002-3374-6699
Christopher M SassettiDepartment of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA Christopher.Sassetti@umassmed.edu.ORCID 0000-0001-6178-4329
University of Massachusetts Chan Medical School · USUniversity of North Carolina at Chapel Hill · US

Funding

Systems Genetics of TuberculosisP01AI132130 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BEHAR, SAMUEL M · 2017 to 2021
$11.2M
Innate Immunity Training ProgramT32AI095213 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SILVERMAN, NEAL · 2011 to 2025
$2.5M
NIAID NIH HHS P01 AI132130NIAID NIH HHS T32 AI095213
6 · The paper itself

Abstract

Host genetics plays an important role in determining the outcome of

Indexed as

AnimalsCollaborative Cross MiceDisease Models, AnimalFemaleGenetic Predisposition to DiseaseGenotypeHumansInterferon-gammaLungMaleMiceMycobacterium tuberculosisQuantitative Trait LociT-LymphocytesTuberculosisInterferon-gammaadaptive immunityCollaborative Cross micehost geneticshost-pathogen interactionshost responseMycobacterium tuberculosis

Identifiers

PMID31772048
PMCPMC6879725
OpenAlexW2991065352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.