Evidence map›Paper›PMID 31772040›Full record

ArticleBJGP open2019

Optimising Management of Patients with Heart Failure with Preserved Ejection Fraction in Primary Care (OPTIMISE-HFpEF): rationale and protocol for a multi-method study.

Faye Forsyth, Jonathan Mant, Clare J Taylor, Fd Richard Hobbs, Carolyn A Chew-Graham, Thomas Blakeman, Emma Sowden, Aaron Long, Muhammad Zakir Hossain, Duncan Edwards and 1 more

Open access · goldAbstract read
In one paragraph

Article in BJGP open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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  11. Understanding the management of heart failure with preserved ejection fraction: a qualitative multiperspective study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Faye ForsythSenior Research Nurse, Primary Care Unit, Department of Public Health & Primary Care, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-2107-3690
Jonathan MantProfessor of Primary Care Research, Primary Care Unit, Department of Public Health & Primary Care, University of Cambridge, Cambridge, UK.
Clare J TaylorGeneral Practitioner and NIHR Academic Clinical Lecturer, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Fd Richard HobbsNuffield Professor of Primary Care Health Sciences, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Carolyn A Chew-GrahamProfessor of General Practice Research, School of Primary, Community and Social Care, Faculty of Medicine and Health Sciences, Keele University, Keele, UK.
Thomas BlakemanClinical Senior Lecturer in Primary Care, Centre for Primary Care, Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, UK.
Emma SowdenResearch Associate, Centre for Primary Care, Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, UK.
Aaron LongAssistant Trial Manager, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Muhammad Zakir HossainResearch Assistant, Health Services Research, School of Primary, Community and Social Care, Faculty of Medicine and Health Sciences, Keele University, Keele, UK.ORCID http://orcid.org/0000-0002-4939-1597
Duncan EdwardsSenior Clinical Research Associate, Primary Care Unit, Department of Public Health & Primary Care, University of Cambridge, Cambridge, UK.
Christi DeatonFlorence Nightingale Foundation Clinical Professor of Nursing, Primary Care Unit, Department of Public Health & Primary Care, University of Cambridge, Cambridge, UK cd531@medschl.cam.ac.uk.
University of Cambridge · GBUniversity of Oxford · GBPrimary Health Care · QAManchester Academic Health Science Centre · GBUniversity of Manchester · GB

Funding

Department of Health IS-SPC-0514-10043Medical Research Council MC_PC_11004
6 · The paper itself

Abstract

backgroundHeart failure with preserved ejection fraction (HFpEF) is less well understood than heart failure with reduced ejection fraction (HFrEF), with greater diagnostic difficulty and management uncertainty.

aimThe primary aim is to develop an optimised programme that is informed by the needs and experiences of people with HFpEF and healthcare providers. This article presents the rationale and protocol for the Optimising Management of Patients with Heart Failure with Preserved Ejection Fraction in Primary Care (OPTIMISE-HFpEF) research programme. DESIGN &

settingThis is a multi-method programme of research conducted in the UK.

methodOPTIMISE-HFpEF is a multi-site programme of research with three distinct work packages (WPs). WP1 is a systematic review of heart failure disease management programmes (HF-DMPs) tested in patients with HFpEF. WP2 has three components (a, b, c) that enable the characteristics, needs, and experiences of people with HFpEF, their carers, and healthcare providers to be understood. Qualitative enquiry (WP2a) with patients and providers will be conducted in three UK sites exploring patient and provider perspectives, with an additional qualitative component (WP2c) in one site to focus on transitions in care and carer perspectives. A longitudinal cohort study (WP2b), recruiting from four UK sites, will allow patients to be characterised and their illness trajectory observed across 1 year of follow-up. Finally, WP3 will synthesise the findings and conduct work to gain consensus on how best to identify and manage this patient group.

resultsResults from the four work packages will be synthesised to produce a summary of key learning points and possible solutions (optimised programme) which will be presented to a broad spectrum of stakeholders to gain consensus on a way forward.

conclusionHFpEF is often described as the greatest unmet need in cardiology. The OPTIMISE-HFpEF programme aims to address this need in primary care, which is arguably the most appropriate setting for managing HFpEF.

Indexed as

agedcardiovascular diseasescare of older peoplegeneral practiceheart failureprimary health careresearch methods (other)

Identifiers

PMID31772040
PMCPMC6995858
OpenAlexW2981664695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.