ArticleBMC veterinary research2019
Antimicrobial resistance patterns and biofilm formation of coagulase-negative Staphylococcus species isolated from subclinical mastitis cow milk samples submitted to the Onderstepoort Milk Laboratory.
Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Epidemiology and antimicrobial resistance of staphylococci other thanFrontiers in veterinary science · 2022Pooled it
- Article
- Virulence genes and antibiotic resistance profiling of staphylococcus species isolated from mastitic dairy cows in and around Bahir dar, Ethiopia.BMC microbiology · 2025Article
- Characterization of T-cell immune responses againstFrontiers in immunology · 2025Article
- Epidemiology and antibiotic resistance of staphylococci on commercial pig farms in Cape Town, South Africa.Scientific reports · 2024Article
- Coagulase-negative staphylococci from bovine milk: Antibiogram profiles and virulent gene detection.BMC microbiology · 2024Article
- A Retrospective Descriptive Study ofAnimals : an open access journal from MDPI · 2024Article
- Antibiograms, multidrug resistance, and milk-related parameters of bacteria isolated from milk of dairy cattle in Phatthalung, Thailand.Veterinary world · 2024Article
- Antimicrobial Resistance Profiles ofAntibiotics (Basel, Switzerland) · 2023Article
- Clinical field trial of parenteral amoxicillin for the treatment of clinical and subclinical mastitis in smallholder dairy farms in the upper region of Northern Thailand.Veterinary world · 2023Article
- Molecular epidemiology and characterization of antimicrobial-resistantFrontiers in cellular and infection microbiology · 2023Article
- Antimicrobial susceptibility of staphylococci from bovine milk samples in routine microbiological mastitis analysis in Finland.Frontiers in veterinary science · 2023Article
- Exploring the distinct immunological reactions of bovine neutrophils towards major and minor pathogens responsible for mastitis.International journal of veterinary science and medicine · 2023Article
- Characterisation of Staphylococci Isolated from Milk Samples of a Water Buffalo Herd.Antibiotics (Basel, Switzerland) · 2022Article
- Characterization of Biofilm Producing Coagulase-Negative Staphylococci Isolated from Bulk Tank Milk.Veterinary sciences · 2022Article
- Comparison between Some Phenotypic and Genotypic Methods for Assessment of Antimicrobial Resistance Trend of Bovine MastitisVeterinary sciences · 2022Article
- Antimicrobial Resistance Profiles and Genes of Staphylococci Isolated from Mastitic Cow's Milk in Kenya.Antibiotics (Basel, Switzerland) · 2021Article
- Detection of Antimicrobial Resistance of BacteriaAntibiotics (Basel, Switzerland) · 2021Article
- High Levels of Antibiotic Resistance in Isolates From Diseased Livestock.Frontiers in veterinary science · 2021Article
- Role of microorganisms isolated from cows with mastitis in Moscow region in biofilm formation.Veterinary world · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreased prevalence of antimicrobial resistance, treatment failure, and financial losses have been reported in dairy cows with coagulase-negative Staphylococcus (CoNS) clinical mastitis, however, studies on CoNS infections are limited in South Africa. Therefore, the objectives of this study were to investigate the antimicrobial resistance patterns and biofilm formation in CoNS isolated from cow milk samples submitted to the Onderstepoort Milk Laboratory.
resultsA total of 142 confirmed CoNS isolates were used for this study. Biofilm formation was identified in 18% of CoNS tested. Staphylococcus chromogenes (11%) had the highest proportion of biofilm formation followed by S. haemolyticus (4.0%), S. epidermidis, S. hominis, S. xylosus, and S. simulans with 1% respectively. Ninety percent (90%) of CoNS were resistant to at least one antimicrobial (AMR) and 51% were multidrug-resistant (MDR). Resistance among CoNS was the highest to ampicillin (90%) and penicillin (89%), few isolates resistant to cefoxitin and vancomycin, 9% respectively. Similarly, MDR-S. haemolyticus (44%), MDR-S. epidermidis (65%), and MDR-S. chromogenes (52%) were mainly resistant to penicillins. The most common resistance patterns observed were resistance to penicillin-ampicillin (16%) and penicillin-ampicillin-erythromycin (10%). Only 42% of biofilm positive CoNS were MDR.
conclusionThe majority of CoNS in this study were resistance to penicillins. In addition, most isolates were β-lactam resistant and MDR. Biofilm formation among the CoNS in this study was uncommon and there was no significant difference in the proportion of MDR-CoNS based on the ability to form a biofilm.
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