Evidence map›Paper›PMID 31771407›Full record

Trial reportAdipocyte2019

Interactions between macro-nutrients' intake, FTO and IRX3 gene expression, and FTO genotype in obese and overweight male adolescents.

Saeid Doaei, Naser Kalantari, Pantea Izadi, Tuire Salonurmi, Alireza Mosavi Jarrahi, Shahram Rafieifar, Ghasem Azizi Tabesh, Ghazaleh Rahimzadeh, Maryam Gholamalizadeh, Mark O Goodarzi

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Adipocyte, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Altered Expression of theNutrients · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. TT Genotype ofNutrients · 2023
    Article
  14. Article
  15. Food technology and biotechnology · 2023
    Review
  16. Article
  17. Review
  18. Association of fat mass and obesity-associated (Journal of diabetes and metabolic disorders · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Saeid DoaeiResearch Center of Health and Environment, Guilan University of Medical Sciences, Rasht, Iran.
Naser KalantariDepartment of Community Nutrition, School of Nutrition and Food Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pantea IzadiDepartment of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tuire SalonurmiDepartment of Internal Medicine, Oulu University Hospital and University of Oulu, Oulu, Finland.
Alireza Mosavi JarrahiFaculty of Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahram RafieifarHealth Promotion and Education Department, Ministry of Health, Tehran, Iran.
Ghasem Azizi TabeshDepartment of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ghazaleh RahimzadehInstitute for Intelligent Systems Research and Innovation (IISRI), Deakin University, Geelong Waurn Ponds, Australia.
Maryam GholamalizadehStudent Research Committee, Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mark O GoodarziDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Shahid Beheshti University of Medical Sciences · IRCedars-Sinai Medical Center · USDeakin University · AUGuilan University of Medical Sciences · IRMinistry of Health and Medical Education · IRTehran University of Medical Sciences · IRUniversity of Oulu · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study is the first to identify the effects of FTO genotype on the interactions between the level of macro-nutrients intake and the expression level of fat mass and obesity associated (FTO) and homeobox transcription factor iriquois-3 (IRX3) genes This longitudinal study was carried out on 84 overweight and obese adolescent boys in Tehran, Iran. The rs9930506 SNP in

Indexed as

Polymorphism, Single NucleotideAdolescentAlpha-Ketoglutarate-Dependent Dioxygenase FTODietary CarbohydratesDown-RegulationGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeHomeodomain ProteinsHumansIranLongitudinal StudiesMaleObesityOverweightTranscription FactorsAlpha-Ketoglutarate-Dependent Dioxygenase FTODietary CarbohydratesFTO protein, humanHomeodomain ProteinsIRX3 protein, humanTranscription FactorscarbohydratefatFTOgenotypeIRX3macronutrientsprotein

Identifiers

PMID31771407
PMCPMC6948981
OpenAlexW2991454264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.