ArticleJournal of dental research2020
Maturation of the Oral Microbiome in Caries-Free Toddlers: A Longitudinal Study.
Article in Journal of dental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Maternal influences on oral microbiome development and implications for early childhood health: a systematic review.Infection and immunity · 2026Pooled it
- Exploring Oral Microbiome in Healthy Infants and Children: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Clinical and microbiological effectiveness of limosilactobacillus reuteri in supportive periodontal therapy: randomized clinical trial.Clinical oral investigations · 2025Trial
- The microbiome of dental and peri-implant subgingival plaque during peri-implant mucositis therapy: A randomized clinical trial.Journal of clinical periodontology · 2022Trial
- Changes in bacterial and metabolic profiles in breastfed infants during dietary transition to solids.Pediatric research · 2026Article
- Oral microbiota composition in children and adults during Spanish COVID-19 lockdown: impact of home self-confinement and SARS-CoV-2 infection.Journal of oral microbiology · 2026Article
- Shifting hormones, shaping health: Gender-affirming therapy & oral care.International journal of transgender health · 2026Article
- Oral microbiome dysbiosis in autism spectrum disorder: the oral-gut-brain axis and future perspectives: a narrative review.Frontiers in microbiology · 2026Review
- Multicohort external validation ofFrontiers in cellular and infection microbiology · 2026Article
- Modelling of the Systemic Inflammatory Host Response in Relation to the Microbiome of the Endodontic Infection.International endodontic journal · 2025Article
- Article
- The Infant Oral Microbiome: Developmental Dynamics, Modulating Factors, and Implications for Oral and Systemic Health.International journal of molecular sciences · 2025Review
- Effect of Daily Vitamin C Supplementation with or Without Flavonoids on Periodontal, Microbial, and Systemic Conditions Before and After Periodontal Therapy: A Case Series from an RCT.Journal of clinical medicine · 2024Article
- Oral Microbiota Development in the First 60 Months: A Longitudinal Study.Journal of dental research · 2024Article
- Effects of clear aligners and traditional removable appliances on oral microbiome in mixed dentition: a comparative study.BMC oral health · 2024Article
- Early life factors and oral microbial signatures define the risk of caries in a Swedish cohort of preschool children.Scientific reports · 2024Article
- Bridging the gap between omics research and dental practice.BDJ open · 2024Review
- A new approach to describe the taxonomic structure of microbiome and its application to assess the relationship between microbial niches.BMC bioinformatics · 2024Article
- Oral microbial changes, oral mucositis and febrile neutropenia during myelosuppressive chemotherapy in patients diagnosed with a solid tumor or lymphoma.Frontiers in oral health · 2024Article
- The oral microbiome of children in health and disease-a literature review.Frontiers in oral health · 2024Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Understanding the development of the oral microbiota in healthy children is of great importance to oral and general health. However, limited data exist on a healthy maturation of the oral microbial ecosystem in children. Moreover, the data are biased by mislabeling "caries-free" populations. Therefore, we aimed to characterize the healthy salivary and dental plaque microbiome in young children. Caries-free (ICDAS [International Caries Detection and Assessment System] score 0) children (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.