ArticleThe Journal of international medical research2020
A persistent outbreak of varicella in a primary school in Dongguan City, Guangdong Province, China.
Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Varicella outbreak at the Itamaraju Indigenous Health Base Center: a descriptive study, Bahia, 2024.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026Article
- Paediatric varicella epidemiology in urban Beijing, China, 2014-2023.Emerging microbes & infections · 2025Article
- Analysis on the epidemiological characteristics of varicella and breakthrough case from 2014 to 2022 in Qingyang City.Human vaccines & immunotherapeutics · 2023Article
- Effectiveness of varicella vaccination during an outbreak in a large one-dose-vaccinated population in Shanghai.Human vaccines & immunotherapeutics · 2022Article
- Vaccine Coverage and Effectiveness in a School-Based Varicella Outbreak in Jinan Prefecture, Shandong Province.Vaccines · 2022Article
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8 authors.
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Abstract
objectivesTo describe the epidemiological features of a school varicella outbreak in Dongguan City, China, to identify the reasons underlying persistent spread, and to assess the effectiveness of the varicella vaccine.
methodsWe identified all cases during the outbreak. We described the outbreak epidemic course and examined the influence of the following variables on the outbreak: sleeping in the dormitory, eating in school, taking school transportation, hand-washing habits, morning examinations, and effectiveness of case isolation. Logistic regression was used to estimate the odds ratio and 95% confidence interval (CI) of contracting varicella.
resultsA total of 92 varicella cases were reported, accounting for 5.53% (92/1663) of all students. Among cases, 64.13% (59/92) were vaccinated. The outbreak lasted for 93 days and occurred in six generations. Vaccination coverage was between 78.05% and 85.67%. The varicella vaccine was effective in 56.63% of recipients (95% CI: 35.49-70.84%). Vaccine effectiveness significantly decreased after 4-6 years.
conclusionsThe varicella vaccine was unable to prevent virus spread even with high vaccination coverage. Delayed and inefficient isolation of cases was the primary cause of the persistent outbreak.
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