Evidence map›Paper›PMID 31771237›Full record

ReviewCancers2019

Molecular Imaging in Pediatric Brain Tumors.

Agostino Chiaravalloti, Luca Filippi, Maria Ricci, Andrea Cimini, Orazio Schillaci

Abstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Head-to-Head Comparison between FDG andDiagnostics (Basel, Switzerland) · 2023
    Review
  4. The Impact of PET/CT on Paediatric Oncology.Diagnostics (Basel, Switzerland) · 2023
    Review
  5. PET/MRI in Pediatric Neuroimaging: Primer for Clinical Practice.AJNR. American journal of neuroradiology · 2022
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Theragnostic Aspects and Radioimmunotherapy in Pediatric Tumors.International journal of molecular sciences · 2020
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Agostino ChiaravallotiDepartment of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-8017-8858
Luca FilippiNuclear Medicine Section, "Santa Maria Goretti" Hospital, 04100 Latina, Italy.
Maria RicciDepartment of Radiological, Oncological and Pathological Sciences, Faculty of Medicine and Surgery, La Sapienza University, 00161 Rome, Italy.ORCID 0000-0002-9277-6337
Andrea CiminiDepartment of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.
Orazio SchillaciDepartment of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decade, several radiopharmaceuticals have been developed and investigated for imaging in vivo of pediatric brain tumors with the aim of exploring peculiar metabolic processes as glucose consumption, amino-acid metabolism, and protein synthesis with nuclear medicine techniques. Although the clinical shreds of evidence are limited, preliminary results are encouraging. In this review, we performed web-based and desktop research summarizing the most relevant findings of the literature published to date on this topic. Particular attention was given to the wide spectrum of nuclear medicine advances and trends in pediatric neurooncology and neurosurgery. Furthermore, the role of somatostatin receptor imaging through single-photon emission computed tomography (SPECT) and positron emission tomography (PET) probes, with reference to their potential therapeutic implications, was examined in the peculiar context. Preliminary results show that functional imaging in pediatric brain tumors might lead to significant improvements in terms of diagnostic accuracy and it could be of help in the management of the disease.

Indexed as

molecular imagingnuclear medicinepediatric brain tumorsPETpositron emission tomographyradiopharmaceuticalssingle-photon emission computed tomographySPECT

Identifiers

PMID31771237
PMCPMC6966547

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.