Evidence map›Paper›PMID 31771152›Full record

ArticleMarine drugs2019

A Natural Quinazoline Derivative from Marine Sponge

Arun Kumar De, Ramachandran Muthiyan, Samiran Mondal, Nilkamal Mahanta, Debasis Bhattacharya, Perumal Ponraj, Kangayan Muniswamy, Anandamoy Kundu, Madhu Sudhan Kundu, Jai Sunder and 4 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Arun Kumar DeICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Ramachandran MuthiyanBioinformatics Centre, ICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Samiran MondalDepartment of Veterinary Pathology, West Bengal University of Animal and Fisheries Sciences, Kolkata 700037, West Bengal, India.
Nilkamal MahantaDepartment of Chemistry and Institute for Genomic Biology, University of Illinois, Urbana Champaign, IL 61801, USA.
Debasis BhattacharyaICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Perumal PonrajICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Kangayan MuniswamyICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Anandamoy KunduICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Madhu Sudhan KunduICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Jai SunderICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Dhanasekar KarunakaranDivision of Social Science, ICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Asit Kumar BeraReservoir and Wetland Fisheries Division, ICAR-Central Inland Fishery Research Institute, Barrackpore, Kolkata 700120, West Bengal, India.
Sibnarayan Dam RoyDivision of Fisheries Sciences, ICAR-Central Island Agricultural Research Institute, Port Blair 744101, Andaman and Nicobar Islands, India.
Dhruba MalakarAnimal Biotechnology Centre, National Dairy Research Institute, Karnal 132001, Haryana, India.
ICAR - Central Island Agricultural Research Institute · INCentral Inland Fisheries Research Institute · INNational Dairy Research Institute · INUniversity of Illinois Urbana-Champaign · USWest Bengal University of Animal and Fishery Sciences · IN

Funding

Department of Biotechnology , Ministry of Science and Technology BT/BI/04/066/2004
6 · The paper itself

Abstract

Here, we report the therapeutic potential of a natural quinazoline derivative (2-chloro-6-phenyl-8H-quinazolino[4,3-b]quinazolin-8-one) isolated from marine sponge

Indexed as

AnimalsApoptosisApoptosis Regulatory ProteinsBreast NeoplasmsCell Line, TumorCell ProliferationCell SurvivalDrug Screening Assays, AntitumorFemaleHumansInhibitory Concentration 50MCF-7 CellsMiceOxidative StressPoriferaQuinazolinesApoptosis Regulatory ProteinsQuinazolinesReactive Oxygen Speciesapoptosisbreast cancermarine spongequinazoline derivativeROS production

Identifiers

PMID31771152
PMCPMC6950652
OpenAlexW2990884970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.