Evidence map›Paper›PMID 31771111›Full record

ArticleMolecules (Basel, Switzerland)2019

Novel Convenient Approach to the Solid-Phase Synthesis of Oligonucleotide Conjugates.

Mariya I Meschaninova, Darya S Novopashina, Olga A Semikolenova, Vladimir N Silnikov, Alya G Venyaminova

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Tandem Oligonucleotide Synthesis Enabled by a Reducible Linker.Chembiochem : a European journal of chemical biology · 2026
    Article
  2. Exploring the Anti-Influenza Activity ofMolecules (Basel, Switzerland) · 2025
    Article
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  14. Tumor Cell-Specific 2'-Fluoro RNA Aptamer Conjugated withInternational journal of molecular sciences · 2021
    Article
  15. Article
  16. Review
  17. Terminal Mono- and Bis-Conjugates of Oligonucleotides withInternational journal of molecular sciences · 2020
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mariya I MeschaninovaInstitute of Chemical Biology and Fundamental Medicine SB RAS, Lavrentiev ave.8, Novosibirsk 630090, Russia.ORCID 0000-0003-0045-2413
Darya S NovopashinaInstitute of Chemical Biology and Fundamental Medicine SB RAS, Lavrentiev ave.8, Novosibirsk 630090, Russia.ORCID 0000-0001-6082-6785
Olga A SemikolenovaDepartment of Natural Sciences, Novosibirsk State University, Pirogova str.2, Novosibirsk 630090, Russia.
Vladimir N SilnikovInstitute of Chemical Biology and Fundamental Medicine SB RAS, Lavrentiev ave.8, Novosibirsk 630090, Russia.
Alya G VenyaminovaInstitute of Chemical Biology and Fundamental Medicine SB RAS, Lavrentiev ave.8, Novosibirsk 630090, Russia.

Funding

Russian Scientific Foundation 19-74-20127Russian State-funded budget project of ICBFM SB RAS АААА-А17-117020210021-7
6 · The paper itself

Abstract

A novel and convenient approach for the solid-phase 5'-functionalization of oligonucleotides is proposed in this article. The approach is based on the activation of free 5'-hydroxyl of polymer support-bound protected oligonucleotides by

Indexed as

Boron CompoundsDiaminesMolecular StructureOligonucleotidesPargylinePropylaminesPyrenesSolid-Phase Synthesis TechniquesBoron CompoundsDiaminesdodecaborateOligonucleotidesPargylinepropargylaminePropylaminespyrenePyrenesamino ligandsboron clustersN,N′-disuccinimidyl carbonate (DSC)oligonucleotide conjugatessolid-phase 5′-functionalization

Identifiers

PMID31771111
PMCPMC6930482

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.