Evidence map›Paper›PMID 31771095›Full record

ArticleMolecules (Basel, Switzerland)2019

Antiviral, Antimicrobial and Antibiofilm Activity of Selenoesters and Selenoanhydrides.

Gabriella Spengler, Annamária Kincses, Tímea Mosolygó, Małgorzata Anna Marć, Márta Nové, Márió Gajdács, Carmen Sanmartín, Helen E McNeil, Jessica M A Blair, Enrique Domínguez-Álvarez

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Organoselenium compounds beyond antioxidants.Future medicinal chemistry · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Colombian Essential Oil ofJournal of fungi (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Gabriella SpenglerDepartment of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Dóm tér 10, 6720 Szeged, Hungary.
Annamária KincsesDepartment of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Dóm tér 10, 6720 Szeged, Hungary.
Tímea MosolygóDepartment of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Dóm tér 10, 6720 Szeged, Hungary.
Małgorzata Anna MarćDepartment of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Dóm tér 10, 6720 Szeged, Hungary.
Márta NovéDepartment of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Dóm tér 10, 6720 Szeged, Hungary.
Márió GajdácsDepartment of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Eötvos utca 6, 6720 Szeged, Hungary.
Carmen SanmartínDepartment of Pharmaceutical Technology and Chemistry, School of Pharmacy and Nutrition, University of Navarra, Irunlarrea 1, 31008 Pamplona, Spain.
Helen E McNeilInstitute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
Jessica M A BlairInstitute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
Enrique Domínguez-ÁlvarezInstituto de Química Orgánica General (IQOG-CSIC), Consejo Superior de Investigaciones Científicas, Juan de la Cierva 3, 28006 Madrid, Spain.
University of Szeged · HUUniversity of Birmingham · GBConsejo Superior de Investigaciones Científicas · ESNavarre Institute of Health Research · ES

Funding

Consejo Superior de Investigaciones Científicas 201780I027Magyar Tudományos Akadémia János Bolyai Research ScholarshipMinistry of Human Capacities of Hungary New National Excellence Program (ÚNKP-18-3)State of Hungary TÁMOP 4.2.4. A/2-11-1-2012-000
6 · The paper itself

Abstract

Selenoesters and the selenium isostere of phthalic anhydride are bioactive selenium compounds with a reported promising activity in cancer, both due to their cytotoxicity and capacity to reverse multidrug resistance. Herein we evaluate the antiviral, the biofilm inhibitory, the antibacterial and the antifungal activities of these compounds. The selenoanhydride and 7 out of the 10 selenoesters were especially potent antiviral agents in Vero cells infected with herpes simplex virus-2 (HSV-2). In addition, the tested selenium derivatives showed interesting antibiofilm activity against

Indexed as

AnimalsAnti-Bacterial AgentsAntifungal AgentsAntiviral AgentsBiofilmsCandidaChlorocebus aethiopsHerpesvirus 2, HumanMolecular StructurePhthalic AnhydridesSalmonella typhimuriumSelenium CompoundsStaphylococcus aureusVero CellsAnti-Bacterial AgentsAntifungal AgentsAntiviral AgentsPhthalic AnhydridesSelenium Compoundsantibacterialsantifungalsantiviralsbiofilm inhibitorsCandida sppHSV-2Salmonella TyphimuriumselenoanhydridesselenoestersStaphylococcus aureus

Identifiers

PMID31771095
PMCPMC6930503
OpenAlexW2991375718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.