Observational studyAmerican journal of ophthalmology2020
Relationship of Corneal Hysteresis and Anterior Lamina Cribrosa Displacement in Glaucoma.
Observational study in American journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Visual Field Progression Rate and Laminar Depth and Curvature in the African Descent and Glaucoma Evaluation Study (ADAGES).Translational vision science & technology · 2026Article
- Corneal Biomechanics in Glaucoma: Current Evidence for Diagnosis, Risk Stratification, and Prognosis.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Lamina cribrosa morphology and clinical implications in glaucoma with thin central corneal thickness.Scientific reports · 2025Article
- Corneal Biomechanical Changes Induced by Chronic Elevated Intraocular Pressure: Implications for Glaucoma Pathogenesis and Management.Journal of ophthalmology · 2025Review
- Corneal stress‒strain index in relation to retinal nerve fibre layer thickness among healthy young adults.Eye (London, England) · 2024Article
- In vivo assessment of the ocular biomechanical properties in patients with idiopathic normal pressure hydrocephalus.International ophthalmology · 2024Article
- Intraocular pressure increases the rate of macular vessel density loss in glaucoma.The British journal of ophthalmology · 2024Observational
- Corneal Biomechanical Measures for Glaucoma: A Clinical Approach.Bioengineering (Basel, Switzerland) · 2023Review
- Relationship between Inter-Eye Asymmetries in Corneal Hysteresis and Visual Field Severity in Patients with Primary Open-Angle Glaucoma.Journal of clinical medicine · 2023Article
- Factors Associated With Visual Acuity Decline in Glaucoma Patients With Loss of Ganglion Cell Complex Thickness.Translational vision science & technology · 2023Article
- Ocular Biomechanics and Glaucoma.Vision (Basel, Switzerland) · 2023Review
- Correlation between Interocular Asymmetry of Corneal Hysteresis and Visual Field Defect in Glaucoma.Korean journal of ophthalmology : KJO · 2023Article
- Article
- A high-accuracy and high-efficiency digital volume correlation method to characterize in-vivo optic nerve head biomechanics from optical coherence tomography.Acta biomaterialia · 2022Article
- Corneal biomechanics: Measurement and structural correlations.Experimental eye research · 2021Review
- Racial Differences in the Rate of Change in Anterior Lamina Cribrosa Surface Depth in the African Descent and Glaucoma Evaluation Study.Investigative ophthalmology & visual science · 2021Article
- Effect of Corneal Hysteresis on the Rates of Microvasculature Loss in Glaucoma.Ophthalmology. GlaucomaObservational
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeTo investigate the relationship between corneal hysteresis (CH) and anterior lamina cribrosa surface (ALCS) displacement over time in a cohort of patients with glaucoma.
designProspective observational case series.
methodsIn this study, 147 eyes from 96 glaucoma or glaucoma suspect patients were followed for a mean of 3.5 years and 7.9 visits. Baseline CH measurements were obtained using the Ocular Response Analyzer (ORA; Reichert Ophthalmic Instruments Inc, Depew, New York, USA). The mean anterior lamina cribrosa surface depth (ALCSD) and choroidal thickness were by automated segmentation of spectral-domain optical coherence tomography (SD-OCT) scans. The rate of change of ALCSD was calculated using linear mixed effects models. Relationship between baseline CH and follow-up ALCSD rate of change was adjusted for confounding factors, including age, intraocular pressure (IOP), and choroidal thickness.
resultsThe mean baseline CH was 9.4 mm Hg (95% confidence interval [CI] 9.1-9.7). Overall, the ALCS was displaced posteriorly at a rate of 0.78 μm/y (95% CI -1.82, 0.26). Seventeen eyes (11.5%) showed a significant posterior displacement of ALCS, whereas 22 eyes (15.0%) showed a significant anterior displacement of ALCS. The choroidal thickness thinned at a rate of -1.09 μm/y during the follow-up (P = .001). Multivariable mixed modeling showed that choroidal thinning, lower IOP change, and lower corneal hysteresis were significantly associated with posterior ALCS displacement over time (P = .034, P = .037, and P = .048). Each 1 mm lower CH was associated with 0.66 μm/y posterior displacement of the ALCS.
conclusionsLower corneal hysteresis was significantly associated with posterior displacement of the anterior lamina cribrosa over time. These data provide additional support for lower corneal hysteresis being a risk factor for glaucoma progression.
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