ArticlePloS one2019
Effects of isotemporal substitution of sedentary behavior with light-intensity or moderate-to-vigorous physical activity on cardiometabolic markers in male adolescents.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Combinations of Physical Activity, Sedentary Behavior, and Sleep Duration and Their Associations With Physical, Psychological, and Educational Outcomes in Children and Adolescents: A Systematic Review.American journal of epidemiology · 2023Pooled it
- Examining the Influence of Promoting Physical Activity Bouts on Adolescent Movement Dispersion: Secondary Analysis of a Randomized Control Trial.Journal for specialists in pediatric nursing : JSPN · 2026Trial
- Validation of Pure and Total Movement Dispersion Variables as Measures of the Distribution of Daily Activity Using Accelerometers: A Secondary Analysis of a Prospective Cohort.Journal of public health (Berlin, Germany) · 2026Article
- Screen time, physical activity, sleep, and depression risk in adolescents: an observational study based on the compositional isotemporal substitution model.Frontiers in public health · 2026Observational
- The Reallocation of Sedentary Time Is Associated with Longitudinal Improvements in Cardiometabolic Outcomes during Childhood.The Journal of pediatrics · 2025Article
- Isotemporal substitution of sedentary time with different physical activity intensities and sleep in obesity parameters across eight latin American countries.Scientific reports · 2025Article
- Isotemporal substitution of physical activity patterns and sitting time with obesity indicators among workers in São Paulo.Scientific reports · 2025Article
- Virtual fitness buddy ecosystem: a mixed reality precision health physical activity intervention for children.NPJ digital medicine · 2024Article
- The associations of physical activity and sedentary behavior with self-rated health in Chinese children and adolescents.PloS one · 2024Article
- Commentary on: "Does light-intensity physical activity moderate the relationship between sitting time and adiposity markers in adolescents?": Commentary on Light-intensity PA, sitting, and adiposity.Journal of sport and health science · 2023Article
- Promoting Health in Pediatric Obesity: A Decade's Research of Physical Activity's Influence on Cardiometabolic Parameters.Medical science monitor : international medical journal of experimental and clinical research · 2023Review
- Making 'being less sedentary feel normal' -investigating ways to reduce adolescent sedentary behaviour at school: a qualitative study.The international journal of behavioral nutrition and physical activity · 2023Article
- Moving beyond moderate-to-vigorous physical activity: the role of light physical activity during adolescence.Frontiers in sports and active living · 2023Article
- Research on the Relationship between Physical Literacy, Physical Activity and Sedentary Behavior.International journal of environmental research and public health · 2022Article
- Dispersion of daily physical activity behaviors in school-age children: A novel approach to measure patterns of physical activity.Journal for specialists in pediatric nursing : JSPN · 2022Article
- Article
- Isotemporal Substitution Analysis of Accelerometer-Derived Sedentary Behavior and Physical Activity on Cardiometabolic Health in Korean Adults: A Population-Based Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- Relationship of Physical Activity and Sedentary Time with Metabolic Health in Children and Adolescents Measured by Accelerometer: A Narrative Review.Healthcare (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing prevalence of sedentary behavior (SB) combined with low levels of physical activity (PA) in children and adolescents has become a growing public health concern. Therefore, this study aimed to identify the daily behavioral pattern of adolescents and examine the isotemporal substitution effects of SB with light-intensity PA (LIPA) or moderate-to-vigorous PA (MVPA) on cardiometabolic markers. In this cross-sectional study, the daily behavioral pattern of Brazilian male adolescents was objectively measured for 7 days. Vector magnitude activity counts were used to estimate SB, LIPA, and MVPA with cut-points specifically validated for youth. The isotemporal substitution model was used to assess the effects of replacing different SB bouts (5, 10, 30, and 60 min) with LIPA or MVPA on cardiometabolic markers [body mass index, waist circumference, body fat percentage (BF%), total cholesterol, high-density lipoprotein cholesterol (HDL-C), non-HDL-C, low-density lipoprotein cholesterol, triglyceride (TG), glucose, insulin, homeostatic model assessment of insulin resistance (HOMA2-IR), insulin sensitivity (HOMA2-S), beta cell function (HOMA2-β), systolic-blood pressure (SBP), diastolic-blood pressure, and cardiometabolic risk score]. Male adolescents (n = 84; age, 16.7 ± 0.9 years) wore the GT3X+ for 6.7 ± 0.6 days, during 15.2 ± 2.3 h, and spent 72.9% of the time in SB, 17.3% in LIPA, and 9.8% in MVPA. SB replacement with LIPA was associated with increased HDL-C, TG, HOMA2-IR, and HOMA2-S and decreased SBP. In contrast, SB replacement with MVPA was associated with decreased BF%. Therefore, our findings suggest that replacing SB with LIPA showed positive results on HDL-C, HOMA2-S and SBP, while replacing SB with MVPA was associated with only one obesity indicator (BF%). Moreover, participants met the daily MVPA recommendations, but they still had a daily behavioral pattern with high SB. In this context, LIPAs can be considered an effective alternative to reduce SB and improve the health indicators of this population.
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