Evidence map›Paper›PMID 31770401›Full record

ArticlePloS one2019

Outcome of patients with heart failure after transcatheter aortic valve implantation.

Ulrich Fischer-Rasokat, Matthias Renker, Christoph Liebetrau, Maren Weferling, Andreas Rolf, Mirko Doss, Helge Möllmann, Thomas Walther, Christian W Hamm, Won-Keun Kim

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ulrich Fischer-RasokatDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.ORCID 0000-0002-7825-2799
Matthias RenkerDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.
Christoph LiebetrauDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.
Maren WeferlingDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.
Andreas RolfDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.
Mirko DossDepartment of Cardiac Surgery, Kerckhoff Heart Center, Bad Nauheim, Germany.
Helge MöllmannDepartment of Cardiology, Medical Clinic I, St. Johannes Hospital, Dortmund, Germany.
Thomas WaltherDepartment of Cardiac Surgery, Kerckhoff Heart Center, Bad Nauheim, Germany.
Christian W HammDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.
Won-Keun KimDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsPatients with aortic stenosis (AS) may have concomitant heart failure (HF) that determines prognosis despite successful transcatheter aortic valve implantation (TAVI). We compared outcomes of TAVI patients with low stroke volume index (SVI) ≤35 ml/m2 body surface area in different HF classes. METHODS AND

resultsPatients treated by transfemoral TAVI at our center (n = 1822) were classified as 1) 'HF with preserved ejection fraction (EF)' (HFpEF, EF ≥50%), 2) 'HF with mid-range EF' (HFmrEF, EF 40-49%), or 3) 'HF with reduced EF' (HFrEF, EF <40%). Patients with SVI >35 ml/m2 served as controls. The prevalence of cardiovascular disease and symptoms increased stepwise from controls (n = 968) to patients with HFpEF (n = 591), HFmrEF (n = 97), and HFrEF (n = 166). Mortality tended to be highest in HFrEF patients 30 days post-procedure, and it became significant after one year: 10.2% (controls), 13.5% (HFpEF), 13.4% (HFmrEF), and 23.5% (HFrEF). However, symptomatic improvement in survivors of all groups was achieved in the majority of patients without differences among groups.

conclusionsPatients with AS and HF benefit from TAVI with respect to symptom alleviation. TAVI in patients with HFpEF and HFmrEF led to an identical, favorable post-procedural prognosis that was significantly better than that of patients with HFrEF, which remains a high-risk population.

Indexed as

AgedAged, 80 and overAortic Valve StenosisBody Mass IndexEchocardiographyFemaleHeart FailureHumansKaplan-Meier EstimateMalePrognosisProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveRetrospective StudiesStroke VolumeTranscatheter Aortic Valve Replacement

Identifiers

PMID31770401
PMCPMC6879149

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.