Evidence map›Paper›PMID 31770250›Full record

ReviewMedicine2019

Gastric mucormycosis complicated by a gastropleural fistula: A case report and review of the literature.

Tomohisa Uchida, Momoko Okamoto, Keita Fujikawa, Daisuke Yoshikawa, Akinari Mizokami, Tomo Mihara, Akira Kondo, Kazuo Ohba, Kazuhiro Kurohama, Masahiro Nakashima and 4 more

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Gastrointestinal mucormycosis byMedical mycology case reports · 2025
    Article
  7. RecurrentMedical mycology case reports · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. An overview of COVID-19 related to fungal infections: what do we know after the first year of pandemic?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  14. Observational
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Tomohisa UchidaDepartment of Rheumatology.
Momoko OkamotoDepartment of Rheumatology.
Keita FujikawaDepartment of Rheumatology.
Daisuke YoshikawaDepartment of Gastroenterology.
Akinari MizokamiDepartment of Rheumatology.
Tomo MiharaDepartment of Infectious Disease, Japan Community Healthcare Organization, Isahaya General Hospital, Isahaya.
Akira KondoDepartment of Infectious Disease, Japan Community Healthcare Organization, Isahaya General Hospital, Isahaya.
Kazuo OhbaDepartment of Gastroenterology.
Kazuhiro KurohamaDepartment of Tumor and Diagnostic Pathology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki.
Masahiro NakashimaDepartment of Tumor and Diagnostic Pathology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki.
Ichiro SekineDepartment of Tumor and Diagnostic Pathology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki.
Shigeki NakamuraDepartment of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Tokyo.
Yoshitsugu MiyazakiDepartment of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Tokyo.
Atsushi KawakamiDepartment of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Nagasaki University · JPJapan Community Healthcare Organization · JPNational Institute of Infectious Diseases · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleMucormycosis is a rare opportunistic fungal infection with poor prognosis. The incidence of mucormycosis has been increasing, and it is a threat to immunocompromised hosts. We present a case of gastric mucormycosis complicated by a gastropleural fistula during immunosuppressive treatment for adult-onset Still disease (AOSD). PATIENT CONCERNS: An 82-year-old woman diagnosed with AOSD who developed gastric ulcers during the administration of an immunosuppressive therapy with corticosteroids, cyclosporine, and tocilizumab complained of melena and epigastralgia. Esophagogastroduodenoscopy showed multiple ulcers covered with grayish or greenish exudates. DIAGNOSES: The patient diagnosed with mucormycosis based on culture and biopsy of the ulcers, which showed nonseptate hyphae branching at wide angles. Mucor indicus was identified using polymerase chain reaction. INTERVENTIONS AND OUTCOMES: Although liposomal amphotericin B was administered, gastric mucormycosis was found to be complicated by a gastropleural fistula. The patient died because of pneumonia due to cytomegalovirus infection, and autopsy revealed the presence of Mucorales around the fistula connecting the stomach and diaphragm. LESSONS: Gastric mucormycosis is refractory to treatment and fatal. Surgical resection, if possible, along with antifungal drugs can result in better outcomes.

Indexed as

Aged, 80 and overFemaleGastric FistulaHumansImmunosuppressive AgentsMucormycosisOpportunistic InfectionsPleuraRespiratory Tract FistulaStill's Disease, Adult-OnsetStomach UlcerImmunosuppressive Agents

Identifiers

PMID31770250
PMCPMC6890297
OpenAlexW2990366016

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.