Evidence map›Paper›PMID 31770123›Full record

ReviewHealth physics2020

Organ Doses from Chest Radiographs in Tuberculosis Patients in Canada and Their Uncertainties in Periods from 1930 to 1969.

David C Kocher, A Iulian Apostoaei, Brian A Thomas, David Borrego, Choonsik Lee, Lydia B Zablotska

Abstract readHistorical ArticleReview
In one paragraph

Review in Health physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David C KocherOak Ridge Center for Risk Analysis, Inc., Oak Ridge, TN.
A Iulian ApostoaeiOak Ridge Center for Risk Analysis, Inc., Oak Ridge, TN.
Brian A ThomasOak Ridge Center for Risk Analysis, Inc., Oak Ridge, TN.
David BorregoRadiation Epidemiology Branch, National Cancer Institute, Bethesda, MD.
Choonsik LeeRadiation Epidemiology Branch, National Cancer Institute, Bethesda, MD.
Lydia B ZablotskaDepartment of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco, CA.

Funding

Studies of Populations Exposed to Diagnostic Medical RadiationZIACP010222 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI KITAHARA, CARI · 2011 to 2025
$13.1M
Canadian Fluoroscopy Cohort Study: Lifespan Mortality and Incidence Follow-UpR01CA197422 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ZABLOTSKA, LYDIA B · 2016 to 2020
$3.4M
NCI NIH HHS R01 CA197422
6 · The paper itself

Abstract

This paper describes a study to estimate absorbed doses to various organs from film-based chest radiographs and their uncertainties in the periods 1930 to 1948, 1949 to 1955, and 1956 to 1969. Estimated organ doses will be used in new analyses of risks of cancer and other diseases in tuberculosis patients in Canada who had chest fluoroscopic and radiographic examinations in those periods. In this paper, doses to lungs, female breast, active bone marrow, and heart from a single chest radiograph in adults and children of ages 1, 5, 10, and 15 y in the Canadian cohort and their uncertainties are estimated using (1) data on the tube voltage (kV), total filtration (mm Al), tube-current exposure-time product (mA s), and tube output (mR [mA s]) in each period; (2) assumptions about patient orientation, distance from the source to the skin of a patient, and film size; and (3) new calculations of sex- and age-specific organ dose conversion coefficients (organ doses per dose in air at skin entrance). Variations in estimated doses to each organ across the three periods are less than 20% in adults and up to about 30% at younger ages. Uncertainties in estimated organ doses are about a factor of 2 to 3 in adults and up to a factor of 4 at younger ages and are due mainly to uncertainties in the tube voltage and tube-current exposure-time product.

Indexed as

AdolescentAdultAge FactorsBone MarrowBreastCanadaChildChild, PreschoolDose-Response Relationship, RadiationFemaleFluoroscopyHeartHistory, 20th CenturyHumansInfantLung

Identifiers

PMID31770123
PMCPMC7246181

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.