ArticleAngewandte Chemie (International ed. in English)2020
Iridium-Catalyzed Hydrochlorination and Hydrobromination of Alkynes by Shuttle Catalysis.
Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Catechol-derived propargyl diol cyclizations with malonyl dichloride: substituent effects on the formation of macrocyclic esters and their hydrochlorinated adducts.RSC advances · 2026Article
- Anti-Markovnikov hydro- and deuterochlorination of unsaturated hydrocarbons using iron photocatalysis.Nature synthesis · 2025Article
- Oxidative hydrolysis of aliphatic bromoalkenes: scope study and reactivity insights.Beilstein journal of organic chemistry · 2024Article
- Mechanistic Investigation of the Rhodium-Catalyzed Transfer Hydroarylation Reaction Involving Reversible C-C Bond Activation.Journal of the American Chemical Society · 2023Article
- Photoinduced Chloroamination Cyclization Cascade withThe Journal of organic chemistry · 2023Article
- Rhodium-Catalyzed Anti-Markovnikov Transfer Hydroiodination of Terminal Alkynes.Angewandte Chemie (International ed. in English) · 2023Article
- Controlling Selectivity in Shuttle Hetero-difunctionalization Reactions: Electrochemical Transfer Halo-thiolation of Alkynes.Angewandte Chemie (International ed. in English) · 2023Article
- Photo-Induced Halogen-Atom Transfer: Generation of Halide Radicals for Selective Hydrohalogenation Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Decarbonylative Transfer Hydrochlorination of Alkenes and Alkynes Based on a B(CAngewandte Chemie (International ed. in English) · 2022Article
- Au(I) Catalyzed HF Transfer: Tandem Alkyne Hydrofluorination and Perfluoroarene Functionalization.ACS catalysis · 2022Article
- Transaminase-Mediated Amine BorrowingOrganic letters · 2022Article
- Palladium-Catalyzed Decarbonylative Iodination of Aryl Carboxylic Acids Enabled by Ligand-Assisted Halide Exchange.Angewandte Chemie (International ed. in English) · 2021Article
- Iridium-Catalyzed Hydrochlorination and Hydrobromination of Alkynes by Shuttle Catalysis.Angewandte Chemie (International ed. in English) · 2020Article
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3 authors.
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Abstract
Described herein are two different methods for the synthesis of vinyl halides by a shuttle catalysis based iridium-catalyzed transfer hydrohalogenation of unactivated alkynes. The use of 4-chlorobutan-2-one or tert-butyl halide as donors of hydrogen halides allows this transformation in the absence of corrosive reagents, such as hydrogen halides or acid chlorides, thus largely improving the functional-group tolerance and safety profile of these reactions compared to the state-of-the-art. This method has granted access to alkenyl halide compounds containing acid-sensitive groups, such as tertiary alcohols, silyl ethers, and acetals. The synthetic value of those methodologies has been demonstrated by gram-scale synthesis where low catalyst loading was achieved.
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