Evidence map›Paper›PMID 31769316›Full record

ArticleFuture medicinal chemistry2020

Methoxyphenol derivatives as reversible inhibitors of myeloperoxidase as potential antiatherosclerotic agents.

Premkumar Jayaraj, Chandrakala A Narasimhulu, Andrei Maiseyeu, Rekha Durairaj, Shashidhar Rao, Sanjay Rajagopalan, Sampath Parthasarathy, Rajagopal Desikan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Premkumar JayarajDepartment of Chemistry, School of Advanced Science, Vellore Institute of Technology, Vellore 632014, India.
Chandrakala A NarasimhuluBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Andrei MaiseyeuCardiovascular Research Institute, Case Western Reserve University, School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, USA.
Rekha DurairajCardiovascular Research Institute, Case Western Reserve University, School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, USA.
Shashidhar RaoDepartment of Chemistry & Chemical Biology, Rutgers University, Piscataway, NJ 08554, USA.
Sanjay RajagopalanCardiovascular Research Institute, Case Western Reserve University, School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106, USA.
Sampath ParthasarathyBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32827, USA.
Rajagopal DesikanCarmel Biosciences, 3562 Habersham at Northlake, Building J, Suite A, Tucker, GA 30084, USA.
Case Western Reserve University · USUniversity of Central Florida · USVellore Institute of Technology University · INRutgers, The State University of New Jersey · USUniversity School · US

Funding

Probing Cardiovascular Actions of GLP-1 Using NanoparticlesR01HL130516 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MAISEYEU, ANDREI · 2016 to 2020
$1.9M
Development of a New Class of Pharmacological Mediators for Myeloperoxidase InhibR43HL103269 · NHLBI · INVASC THERAPEUTICS, INC. · PI RAJAGOPAL, DESIKAN · 2010 to 2010
$200k
Alpha Lipoic Acid Derivatives for Treatment of HypertensionR43HL103350 · NHLBI · INVASC THERAPEUTICS, INC. · PI RAJAGOPAL, DESIKAN · 2010 to 2010
$191k
NHLBI NIH HHS R01 HL130516NHLBI NIH HHS R43 HL103269NHLBI NIH HHS R43 HL103350
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ArteriosclerosisCoumaric AcidsEnzyme InhibitorsHumansMolecular Docking SimulationMolecular StructureOxidation-ReductionPeroxidasePhenolsCoumaric AcidsEnzyme Inhibitorsferulic acidPeroxidasePhenolscardiovascularferulic acidHDLhypochlorous acidLDLmethoxyphenolmyeloperoxidaseproline

Identifiers

PMID31769316
PMCPMC7333589
OpenAlexW2989740435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.