Evidence map›Paper›PMID 31769280›Full record

ArticleACS infectious diseases2020

Substrate Tolerance of Bacterial Glycosyltransferase MurG: Novel Fluorescence-Based Assays.

Katsuhiko Mitachi, Hyun Gi Yun, Cody D Gillman, Karolina Skorupinska-Tudek, Ewa Swiezewska, William M Clemons, Michio Kurosu

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Katsuhiko MitachiDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, Tennessee 38163, United States.ORCID 0000-0002-6897-8959
Hyun Gi YunDivision of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, California 91125, United States.ORCID 0000-0002-3508-5791
Cody D GillmanDivision of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, California 91125, United States.ORCID 0000-0002-3548-9200
Karolina Skorupinska-TudekDepartment of Lipid Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warszawa, Poland.ORCID 0000-0002-3472-2517
Ewa SwiezewskaDepartment of Lipid Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warszawa, Poland.ORCID 0000-0002-3439-8948
William M ClemonsDivision of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Blvd., Pasadena, California 91125, United States.ORCID 0000-0002-0021-889X
Michio KurosuDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, Tennessee 38163, United States.ORCID 0000-0003-0092-0619
California Institute of Technology · USInstitute of Biochemistry and Biophysics, Polish Academy of Sciences · PLUniversity of Tennessee Health Science Center · US

Funding

Mechanistic details of key integral-membrane enzymes for antimicrobial discoveryR01GM114611 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI William M. Clemons, Michio Kurosu · 2016 to 2026
$4.2M
NIGMS NIH HHS R01 GM114611
6 · The paper itself

Abstract

MurG (uridine diphosphate-

Indexed as

GlycosyltransferasesTransferasesAnti-Bacterial AgentsFluorescenceAnti-Bacterial AgentsGlycosyltransferasesTransferasesfluorescence-based assaylipid Ilipid IIMraY translocase IMurG translocase IIPark’s nucleotideristocetin

Identifiers

PMID31769280
PMCPMC7286788
OpenAlexW2990203748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.