Evidence map›Paper›PMID 31769230›Full record

Trial reportCancer medicine2020

Radiomics based on

Xuejin Ou, Jing Zhang, Jian Wang, Fuwen Pang, Yongsheng Wang, Xiawei Wei, Xuelei Ma

Abstract readClinical Trial
In one paragraph

Trial report in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Diagnostic Value ofTechnology in cancer research & treatment
    Pooled it
  4. Trial
  5. Radiomics based onCancer medicine · 2020
    Trial
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
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  14. Hype or hope? A review of challenges in balancing tumor control and treatment toxicity in breast cancer from the perspective of the radiation oncologist.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
  15. Clinical application ofJapanese journal of radiology · 2024
    Review
  16. Semiquantitative 2-[Frontiers in medicine · 2024
    Review
  17. PrognosticDiagnostics (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuejin OuDepartment of Biotherapy, West China Hospital and State Key Laboratory of Biotherapy, Sichuan University, Chengdu, PR China.
Jing ZhangState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, PR China.
Jian WangSchool of Computer Science, Nanjing University of Science and Technology, Nanjing, PR China.
Fuwen PangDepartment of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, P.R. China.
Yongsheng WangDepartment of Thoracic Oncology, West China Hospital, Sichuan University, Chengdu, PR China.
Xiawei WeiLaboratory of Aging Research and Nanotoxicology, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Xuelei MaDepartment of Biotherapy, West China Hospital and State Key Laboratory of Biotherapy, Sichuan University, Chengdu, PR China.ORCID 0000-0002-9148-5001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur study assessed the ability

methodsSixty-five breast nodules from 44 patients diagnosed as breast carcinoma or breast lymphoma were included. Standardized uptake value (SUV) and radiomic features from CT and PET images were extracted using local image features extraction software. Six discriminative models including PETa (based on clinical, SUV and radiomic features from PET images), PETb (SUV and radiomic features from PET images), PETc (radiomic features only from PET images), CTa (clinical and radiomic features from CT images), CTb (radiomic features only from CT images), and SUV model were generated using least absolute shrinkage and selection operator method and linear discriminant analysis. The areas under the receiver operating characteristic curve (AUCs), accuracy, sensitivity, and specificity were calculated to evaluate the discriminative ability of these models.

resultsPETa and CTa models showed the best ability to differentiation in training and validation group (AUCs of 0.867 and 0.806 for PETa model, AUCs of 0.891 and 0.759 for CTa model, respectively).

conclusionModels based on clinical, SUV, and radiomic features of

Indexed as

Machine LearningAdultAgedAged, 80 and overBreast NeoplasmsDiagnosis, DifferentialFemaleFluorodeoxyglucose F18Follow-Up StudiesHumansImage Processing, Computer-AssistedLymphomaMiddle AgedPositron Emission Tomography Computed TomographyPrognosisRadiopharmaceuticalsFluorodeoxyglucose F18Radiopharmaceuticalsbreast lymphomadiagnosislinear discriminant analysismachine-learningradiomic

Identifiers

PMID31769230
PMCPMC6970046

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.