Evidence map›Paper›PMID 31769113›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2020

Alcohol intake and Parkinson's disease risk in the million women study.

Iris Y Kim, TienYu Owen Yang, Alicia K Heath, Rachel F Simpson, Gillian K Reeves, Jane Green, Sarah Floud, Anna Brown, David J Hunter, Valerie Beral and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Association between alcohol consumption and mortality in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
  5. Epidemiology of Parkinson's Disease: An Update.Current neurology and neuroscience reports · 2024
    Review
  6. Epigenetic associations ofFrontiers in psychiatry · 2024
    Article
  7. Life style and Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2022
    Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Iris Y KimDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
TienYu Owen YangNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Alicia K HeathSchool of Public Health, Imperial College London, London, United Kingdom.
Rachel F SimpsonNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Gillian K ReevesNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Jane GreenNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Sarah FloudNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Anna BrownNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
David J HunterDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Valerie BeralNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Siân SweetlandNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
Million Women Study Collaborators

Funding

Cancer Research UK 16491Cancer Research UK C570/A16491Medical Research Council MR/K02700X/1
6 · The paper itself

Abstract

backgroundAlcohol intake may be associated with a lower risk of Parkinson's disease (PD), but findings from previous studies have been inconclusive.

objectiveTo determine the association between alcohol intake and PD risk in the Million Women Study, a large, prospective study of women in the UK.

methodsBetween 1996 and 2001, approximately 1.3 million women in the UK, mean age 56 (standard deviation, 5) years, were recruited into the Million Women Study. Information on alcohol intake, lifestyle factors, and medical history was collected at recruitment by questionnaire. Information on incident cases of PD was ascertained by record linkage to national hospital admission records and death registrations. We estimated multivariable-adjusted relative risks and corresponding 95% confidence intervals using Cox proportional hazards models according to categories of alcohol intake.

resultsDuring an average of 17.9 years of follow-up, 11,009 women had a new record of PD among 1,309,267 women. In drinkers, the multivariable-adjusted relative risk comparing women who drank more than 14 drinks of alcohol per week with women who drank 1 to 2 drinks of alcohol per week was 0.99 (95% confidence interval: 0.90, 1.10). Results did not materially change after excluding the first 10 years of follow-up (relative risk

conclusionThese results do not support an association between alcohol intake and PD risk in women. © 2019 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.

Indexed as

Parkinson DiseaseAlcohol DrinkingFemaleHumansMiddle AgedProportional Hazards ModelsProspective StudiesRiskRisk FactorsalcoholMillion Women StudyParkinson's diseaseprospective studies

Identifiers

PMID31769113
PMCPMC7155013

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.