Evidence map›Paper›PMID 31769047›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2020

Externalising pathways to alcohol-related problems in emerging adulthood.

Gemma Hammerton, Alexis C Edwards, Liam Mahedy, Joseph Murray, Barbara Maughan, Kenneth S Kendler, Matthew Hickman, Jon Heron

Abstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Childhood conduct problems, potential snares in adolescence, and problematic substance use in Brazil.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gemma HammertonPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Alexis C EdwardsVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Liam MahedyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Joseph MurrayPostgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Barbara MaughanMRC Social, Genetic & Developmental Psychiatry Centre, King's College London, London, UK.
Kenneth S KendlerVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
Matthew HickmanPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Jon HeronPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Funding

Pathways to Alcohol Use Disorders in ALSPAC: A Genetic-Developmental StudyR01AA018333 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M, KENDLER, KENNETH SEEDMAN · 2010 to 2014
$2.8M
Genetic influences on developmental heterogeneity of alcohol use disorderK01AA021399 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI EDWARDS, ALEXIS C · 2012 to 2016
$707k
British Heart FoundationCancer Research UKDepartment of HealthMedical Research Council G0800612Medical Research Council G0800612/86812Medical Research Council G0802736Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MC_UU_00011/7Medical Research Council MR/KO232331/1Medical Research Council MR/L022206/1NIAAA NIH HHS K01 AA021399NIAAA NIH HHS R01 AA018333NIH HHS K01AA021399NIH HHS PD301198-SC10164NIH HHS R01AA018333Wellcome TrustWellcome Trust 102215/2/13/2Wellcome Trust 209138/Z/17/Z
6 · The paper itself

Abstract

backgroundBoth 'early-onset persistent' and 'adolescent-onset' conduct problems (CPs) are associated with alcohol-related problems in emerging adulthood. The escalation of early CPs into criminal behaviour and heavy alcohol consumption prior to emerging adulthood are both likely to be important pathways.

methodsData were analysed from 3,038 young people in a UK birth cohort, the Avon Longitudinal Study of Parents and Children. The exposure was developmental trajectories of CPs ('low', 'childhood-limited', 'adolescent-onset' and 'early-onset persistent') between ages 4 and 13 years. The mediator was latent classes representing heavy alcohol consumption and/ or criminal behaviour at age 15 years. For the outcome, a quadratic latent growth curve was estimated to capture nonlinear change in alcohol-related problems between ages 18 and 23 years.

resultsThose with 'early-onset persistent' [b(95% CI) = 1.16 (0.17, 2.14)] and 'adolescent-onset' CPs [b(95% CI) = 1.31 (0.17, 2.45)] had higher levels of alcohol-related problems at age 18 years compared to those with 'low' CPs', but there was little evidence of an association with alcohol-related problems after age 19 years. There was evidence for an indirect effect of 'early-onset persistent' CPs [b(95% CI) = 1.12 (0.52, 1.72)] on alcohol-related problems at age 18 years via the latent classes of alcohol and criminal behaviour in adolescence. This was not found for 'adolescent-onset' CPs [b(95% CI) = 0.35 (-0.36, 1.07)].

conclusionsStrong associations exist between early CPs, adolescent alcohol consumption and criminal behaviour and alcohol-related problems at age 18 years. Associations between early CPs and alcohol-related problems weakened considerably across emerging adulthood.

Indexed as

AdolescentAlcohol-Related DisordersFemaleHumansLongitudinal StudiesMaleProblem BehaviorRisk FactorsUnderage DrinkingYoung Adultalcohol-related problemsAvon Longitudinal Study of Parents and Childrenconduct problemscriminal behaviourmediation

Identifiers

PMID31769047
PMCPMC7242151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.