Evidence map›Paper›PMID 31768964›Full record

Observational studyJournal of racial and ethnic health disparities2020

Pathologic Factors Affecting Colorectal Cancer Survival in a Jamaican Population-the UHWI Experience.

Patrick O Roberts, Tamara G de Souza, Brian M Grant, Matthew G Wanliss, Pierre-Anthony E Leake, Ayesha R Johnson, Hilary A Brown, Joseph M Plummer, Rory K Thompson

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of racial and ethnic health disparities, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. The Role of lncRNA PCAT6 in Cancers.Frontiers in oncology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Patrick O RobertsDepartment of Surgery, Radiology, Anaesthetics & Intensive Care, University of the West Indies (Mona Campus), Kingston, Jamaica.
Tamara G de SouzaDepartment of Pharmacology, St. George's University, School of Medicine, True Blue, Grenada.
Brian M GrantDepartment of Surgery, Howard University, Washington, DC, USA.
Matthew G WanlissDepartment of Surgery, Radiology, Anaesthetics & Intensive Care, University of the West Indies (Mona Campus), Kingston, Jamaica.
Pierre-Anthony E LeakeDepartment of Surgery, Radiology, Anaesthetics & Intensive Care, University of the West Indies (Mona Campus), Kingston, Jamaica.
Ayesha R JohnsonFlorida Department of Health, 4052 Bald Cypress Way, Tallahassee, FL, 32399, USA.
Hilary A BrownDepartment of Surgery, Radiology, Anaesthetics & Intensive Care, University of the West Indies (Mona Campus), Kingston, Jamaica.
Joseph M PlummerDepartment of Surgery, Radiology, Anaesthetics & Intensive Care, University of the West Indies (Mona Campus), Kingston, Jamaica.
Rory K ThompsonDepartment of Pathology, University of the West Indies (Mona Campus), Mona, Jamaica. rorykthompson@gmail.com.ORCID 0000-0002-5106-4915
University of the West Indies System · JMFlorida Department of Health · USHoward University · USSt. George's University · GD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveColorectal carcinoma (CRC) is the third most common cancer and a leading cause of cancer-related deaths in Jamaica. Globally, CRC mortality rates have been decreasing in developed countries; however, CRC mortality rates are trending upwards in low-income or developing countries. Our objectives are to estimate the overall 5-year survival and to determine the pathologic factors associated with overall survival of colorectal adenocarcinoma after surgery at the University Hospital of the West Indies (UHWI).

methodsRetrospective, observational (cross-sectional) study on CRC patients. We summarized and analyzed demographic, clinical data, histopathological data, and survival rates. Single predictor Cox regression models were used to establish associations between survival and specified clinicopathological characteristics.

resultsA total of 217 patients who underwent operative resection of colorectal adenocarcinoma from January 2004 to December 2013. Median survival time post-therapeutic intervention was 48 months. Late stage at diagnosis, positive circumferential resection margins, neural and vascular invasion, as well as three or more nodal metastases were all associated with statistically significant worsened outcome.

conclusionsDespite surgical quality meeting USA standards, CRC survival rates in Jamaica are 13% lower than survival of CRC in non-Hispanic Blacks in the USA. The survival trends found by our study support the application of international indices for CRC prognostication to Jamaican patients.

Indexed as

AdenocarcinomaAdultAgedAged, 80 and overColorectal NeoplasmsCross-Sectional StudiesFemaleForecastingHumansJamaicaMaleMiddle AgedRetrospective StudiesSurvival RateColorectal cancerJamaicaPathologic factorsSurvival

Identifiers

PMID31768964
OpenAlexW2990497141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.