Evidence map›Paper›PMID 31768953›Full record

ArticleEnvironmental science and pollution research international2020

Prenatal exposure to organophosphate pesticides, maternal paraoxonase 1 genotype, and childhood neurodevelopment at 24 months of age in Shandong, China.

Yiwen Wang, Yan Zhang, Lin Ji, Yijun Zhou, Rong Shi, Michihiro Kamijima, Jun Ueyama, Yu Gao, Ying Tian

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yiwen WangMOE and Shanghai Key Laboratory of Children's Environmental Health, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China.
Yan ZhangDepartment of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lin JiDepartment of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yijun ZhouDepartment of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Rong ShiDepartment of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Michihiro KamijimaDepartment of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, 467-8601, Japan.
Jun UeyamaDepartment of Pathophysiological Laboratory Sciences, Field of Radiological and Medical Laboratory Sciences, Nagoya University, Nagoya, Aichi, 461-8673, Japan.
Yu GaoDepartment of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China. gaoyu_ciel@sjtu.edu.cn.
Ying TianMOE and Shanghai Key Laboratory of Children's Environmental Health, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China. tianmiejp@sjtu.edu.cn.
Shanghai Jiao Tong University · CNNagoya City University · JPNagoya University · JP

Funding

National Key Research and Development Program of China 2016YFC1000203National Key Research and Development Program of China 2017YFC1600500National Natural Science Foundation of China 81602823National Natural Science Foundation of China 81630085National Natural Science Foundation of China 81773387National Natural Science Foundation of China 81803185National Natural Science Foundation of China 81872629Scientific research program of Shanghai Municipal Commission of Health and Family Planning 201640174Scientific research program of Shanghai Municipal Commission of Health and Family Planning 201840180the Science and Technology Commission of Shanghai Municipality 17ZR1415800
6 · The paper itself

Abstract

Prenatal organophosphate pesticide (OP) exposure was reported to negatively affect childhood neurodevelopment. Paraoxonase 1 (PON1) is a key enzyme in the metabolism of OPs and may affect an individual's susceptibility to OP exposure. However, little is known about its role in the associations of prenatal OP exposure and childhood neurodevelopment. We measured dimethylphosphate (DM), diethylphosphate (DE), and total dialkylphosphate (DAP) metabolites in maternal urine (n = 436) as well as PON1

Indexed as

Child DevelopmentPrenatal Exposure Delayed EffectsAdultAryldialkylphosphataseChinaFemaleGenotypeHumansInfantMaleMaternal ExposureOrganophosphatesPesticidesPregnancyAryldialkylphosphataseOrganophosphatesPesticidesPON1 protein, humanChinaNeurodevelopmentOrganophosphate pesticidesParaoxonase 1Prenatal exposure

Identifiers

PMID31768953
OpenAlexW2991623019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.