Evidence map›Paper›PMID 31768438›Full record

ArticleHeliyon2019

Synthesis, antibacterial activity and molecular docking study of vanillin derived 1,4-disubstituted 1,2,3-triazoles as inhibitors of bacterial DNA synthesis.

Mumtaz Hussain, Tahir Qadri, Zahid Hussain, Aamer Saeed, Pervaiz Ali Channar, Syeda Aaliya Shehzadi, Mubashir Hassan, Fayaz Ali Larik, Tarique Mahmood, Arif Malik

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. An ortho-rhom-bic polymorph of isavuconazole.Acta crystallographica. Section E, Crystallographic communications · 2025
    Article
  5. Article
  6. Biochemical Screening,Current pharmaceutical biotechnology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Triazole analogues as potential pharmacological agents: a brief review.Future journal of pharmaceutical sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Mumtaz HussainDepartment of Chemistry, University of Karachi, 75270, Karachi, Pakistan.
Tahir QadriDepartment of Chemistry, University of Karachi, 75270, Karachi, Pakistan.
Zahid HussainDepartment of Chemistry, University of Karachi, 75270, Karachi, Pakistan.
Aamer SaeedDepartment of Chemistry, Quaid-i-Azam University, 45320, Islamabad, Pakistan.
Pervaiz Ali ChannarDepartment of Chemistry, Quaid-i-Azam University, 45320, Islamabad, Pakistan.
Syeda Aaliya ShehzadiSulaiman Bin Abdullah Aba Al-Khail-Centre for Interdisciplinary Research in Basic Sciences (SA-CIRBS), International Islamic University, 44000, Islamabad, Pakistan.
Mubashir HassanInstitute of Molecular Biology and Biotechnology, The University of Lahore, Defence Road Campus, Lahore, Pakistan.
Fayaz Ali LarikDepartment of Chemistry, Quaid-i-Azam University, 45320, Islamabad, Pakistan.
Tarique MahmoodDepartment of Chemistry, University of Karachi, 75270, Karachi, Pakistan.
Arif MalikInstitute of Molecular Biology and Biotechnology, The University of Lahore, Defence Road Campus, Lahore, Pakistan.
University of Karachi · PKQuaid-i-Azam University · PKUniversity of Lahore · PKInternational Islamic University, Islamabad · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) compelled scientists in general while pharmacists, chemists and biologists in specific to believe that we could always remain ahead of the pathogens. The pipeline of new drugs is running gasping and the inducements to develop new antimicrobials to address the global problems of drug resistance are weak. In this pursuit, effective endeavours to prepare new anti-bacterial entities is highly wished. The present study demonstrates successful synthesis of a library of 1,4-disbustituted 1,2,3-triazoles (

Indexed as

1,4-Disubstituted 1,2,3-triazolesAntibacterial agentsClick chemistryMolecular dockingOrganic chemistryPharmaceutical chemistryThymidylate kinase (TMPK) inhibitors

Identifiers

PMID31768438
PMCPMC6872831
OpenAlexW2991637586

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.