ArticleKidney diseases (Basel, Switzerland)2019
A Global Evolutionary Trend of the Frequency of Primary Glomerulonephritis over the Past Four Decades.
Article in Kidney diseases (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 43 citations in OpenAlex.
- Targeting the B-Cell Activating Factor and a Proliferation-Inducing Ligand Pathway in IgAN: From Disease Pathogenesis to Clinical Trial Evidence.Kidney international reports · 2026Review
- The Spectrum and Temporal Trends of Glomerular Diseases in Saudi Arabia: A Systematic Review of Biopsy-Based Studies.International journal of nephrology · 2026Review
- IgA nephropathy: a novel pathway in immunopathogenesis dependent on the timing of Epstein-Barr virus infection.Frontiers in immunology · 2026Review
- Global and China trends in glomerulonephritis-induced chronic kidney disease: health inequities, risk factors and projections to 2050.Renal failure · 2025Article
- Aetiology of acute/subacute nephritic syndrome: results from kidney biopsy registries in Japan and Europe.BMC nephrology · 2025Article
- The burden of chronic kidney disease in Asia region: a review of the evidence, current challenges, and future directions.Kidney research and clinical practice · 2025Article
- Regulatory role of the mTOR signaling pathway in autophagy and mesangial proliferation in IgA nephropathy.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- Article
- Five-Year study on renal outcomes in biopsy-proven focal segmental glomerulosclerosis patients in Shiraz, Iran.Caspian journal of internal medicine · 2024Article
- How to Choose the Right Treatment for Membranous Nephropathy.Medicina (Kaunas, Lithuania) · 2023Review
- Years of life lost and long-term outcomes due to glomerular disease in a Southeast Asian Cohort.Scientific reports · 2023Observational
- The incidence and prevalence of IgA nephropathy in Europe.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Review
- The Effects ofPharmaceuticals (Basel, Switzerland) · 2023Review
- Individualizing immunosuppressive therapy decision in immunoglobulin A nephropathy and application in a Southeast Asian cohort.Clinical kidney journal · 2022Article
- A Descriptive Evaluation of Health Literacy and Determinants of COVID-19 Vaccine Acceptance among Patients with IgA Nephropathy with High Vaccine Uptake.Glomerular diseases · 2022Article
- Epidemiology of native kidney disease in Flanders: results from the FCGG kidney biopsy registry.Clinical kidney journal · 2022Article
- Morphological Spectrum of Glomerulonephritis in Medical Renal Biopsies: A Single-Center Study.Cureus · 2022Article
- Epidemiological characteristics and pathological changes of primary glomerular diseases.PloS one · 2022Article
- The IRE1α pathway in glomerular diseases: The unfolded protein response and beyond.Frontiers in molecular medicine · 2022Review
- A Comprehensive Review Study on Glomerulonephritis Associated With Post-streptococcal Infection.Cureus · 2021Review
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe pattern of glomerulonephritis (GN) in Singapore is compared with that of 19 other countries to review changing trends in the evolution of GN in Asian, Eastern, and Western countries.
methodThree thousand two hundred and eighty-nine renal biopsies in Singapore were reviewed and compared with that of 19 other countries.
resultsIgA nephritis is on the decline in many countries, including Singapore, though it still remains the commonest GN in Singapore. Membranous GN that if used to be more frequently present in Western countries has also declined though it continues a rising trend in countries such as Singapore and China. Worldwide, the frequency of focal sclerosing glomerulosclerosis (FSGS) continues to increase in many countries, but in some countries, the frequency is still low with mesangiocapillary GN remaining indigenous.
conclusionUrbanization and socioeconomic changes and less exposure to parasitic and other infestations have transformed Singapore's pattern, which is tending toward that of more developed countries. Antigenic exposure due to lifestyle changes, environmental, and industrial pollution are significant contributory factors that affect the evolutionary trend of GN in many countries. The rising trend in the frequency of FSGS may reflect aging and obesity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.