Triacontanoic ester of 5''-hydroxyjustisolin: Tumour suppressive role in cervical cancer via Bcl-2, BAX and caspase-3 mediated signalling.

Litty Joseph, K K Srinivasan

Open access · goldAbstract read

In one paragraph

Article in Toxicology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

0.9field-weighted citation impact, top 25% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

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The Characters of Graphene Oxide Nanoparticles and Doxorubicin Against HCT-116 Colorectal Cancer Cells In Vitro.Journal of gastrointestinal cancer · 2022
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Resveratrol exhibits neuroprotection against paraquat-induced PC12 cells via heme oxygenase 1 upregulation by decreasing MiR-136-5p expression.Bioengineered · 2022
Article
Upregulation of DR5 and Downregulation of Survivin by IITZ-01, Lysosomotropic Autophagy Inhibitor, Potentiates TRAIL-Mediated Apoptosis in Renal Cancer Cells via Ubiquitin-Proteasome Pathway.Cancers · 2020
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Litty JosephDepartment of Pharmaceutical Sciences, Centre for Professional and Advanced studies, Cheruvandoor Campus, Ettumanoor PO, Kottayam, 686 631, Kerala, India.

K K SrinivasanDepartment of Chemistry, Shri Madhwa Vadiraja Institute of Technology and Management, Bantakal, Udupi, 574 115, Karnataka, India.

Institute of Technology Management · INMahatma Gandhi University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triacontanoic ester of 5"-hydroxyjustisolin, a lignan from

Indexed as

AntitumorBAXBcl-2Caspase-3DLA, Daltons lymphoma ascitesDMEM, Dulbecco's modified eagle's mediumDMSO, dimethyl suphoxideFBS, fetal bovine serumHaCat, human keratinocyte immortalisedHeLa, human cervical carcinomaJusticia simplex D. DonMCF-7, human breast adenocarcinoma cell lineMTT, methyl tetrazolium assayRT-PCR, reverse transcriptase polymerize chain reactionTE5-OHJ, triacontanoic ester of 5ʹʹ-hydroxyjustisolinTriacontanoic ester of 5ʺ -hydroxyjustisolin

Identifiers

PMID31768331

DOI10.1016/j.toxrep.2019.10.015

PMCPMC6872787

OpenAlexW2985515336

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.