Evidence map›Paper›PMID 31768318›Full record

ArticleAsian journal of urology2019

Comparative assessment of efficacy and safety of different treatment for

Shi Qiu, Siwei Bi, Tianhai Lin, Zhuheng Wu, Qi'an Jiang, Jiwen Geng, Liangren Liu, Yige Bao, Xiang Tu, Mingjing He and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Asian journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Shi QiuDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Siwei BiDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Tianhai LinDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Zhuheng WuDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Qi'an JiangDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Jiwen GengDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Liangren LiuDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Yige BaoDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Xiang TuDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Mingjing HeDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Lu YangDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Qiang WeiDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare these managements focusing on the efficacy and safety to treat overactive bladder (OAB) in children through network meta-analysis (NMA).

methodsWe searched PubMed, Embase, the Cochrane Library Central Register of Controlled Trials (CENTRAL) and the reference lists up to May 1st, 2017. Data from eligible randomized controlled trails (RCT) studies including three different treatment options were extracted. The primary outcome was maximal voiding volume (MVV). We performed pairwise meta-analyses by random effects model and NMA by Bayesian model. We used the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) framework to assess the quality of evidence contributing to each network estimate.

resultsSix RCTs (462 patients) comparing three different interventions fulfilled the inclusion criteria. A low risk of bias was shown for the majority of the study items. The results of NMA showed that compared with antimuscarinic drugs, Parasacral transcutaneous electrical nerve stimulation was associated with significant improvement in the MVV (mean difference [MD] = 58.50, 95% confidential interval [CI]: 45.95-69.52), followed by urotherapy group (MD = 21.03, 95% CI: 11.85-29.97). When it comes to the constipation, antimuscarinic drugs exerted significant benefit than PTENS (odds ratio [OR]: 0.22, 95% CI: 0.01-0.46). No significant difference was found between other treatments.

conclusionCompared with antimuscarinic drugs, PTENS was associated with significant better efficacy considering MVV, but more constipation events in

Indexed as

AnticholinergicsMeta-analysisOveractive bladderParasacral transcutaneous electrical nerve stimulation

Identifiers

PMID31768318
PMCPMC6872791
OpenAlexW2936659860

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.